1 / 14

OPTI CCA-TS-lactate

OPTI CCA-TS-lactate. Lactate. What is lactate?. Produced by cells during anaerobic glycolysis. Normal Range: 0.5 to 2.2 mmol/L. High lactate levels: >4mmol/L May rise in severe exercise to 20 mmol/L. Lactate. What is lactic acidosis?. Processed by the liver and kidneys.

ciara-palmer
Download Presentation

OPTI CCA-TS-lactate

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. OPTI CCA-TS-lactate

  2. Lactate What is lactate? Produced by cells during anaerobic glycolysis. Normal Range: 0.5 to 2.2 mmol/L. High lactate levels: >4mmol/L May rise in severe exercise to 20 mmol/L

  3. Lactate What is lactic acidosis? Processed by the liver and kidneys. Lactic acidosis is when H+ ions build up leading to a drop in pH. The following symptoms appear with lactate levels above 4 mmol/L: increased heart rate increased respiratory rate alteration in mental status.

  4. Types of lactic acidosis Type A lactic acidosis is associated with hypoperfusion or hypoxia. It is usually a feature of acute critical illness. Type B lactic acidosis is caused by conditions that increase the amount of lactate/lactic acid in the blood. Occurs with adequate tissue oxygenation and normal hemodynamics (blood pressure, volume, etc.) Lactic acidosis is separated into two types: A and B.

  5. Lactate Where is lactate tested? In ER: When a patient has the following symptoms: shortness of breath rapid breathing paleness sweating muscle weakness stomach pain

  6. Lactate Where is lactate tested? Intensive Care Unit: When a patient presents with following conditions suspected shock heart attack congestive heart failure sepsis uncontrolled diabetes inadequate oxygenation of tissues

  7. Lactate What is the clinical significance of lactate? Lactate is a precursor to sepsis- life threatening blood infection Lactate is good prognosticator of morbidity (death rate) and mortality (death). The greater the increase in lactate, the greater the mortality.

  8. What is the clinical significance of lactate? In a study of 1278 patients with infection, mortality was 4.9% among those whose lactate was less than 2.5 mmol/L on admission compared with 28.4% among those whose lactate was >4mmol/L.

  9. Lactate with ABG Why test lactate with ABGs? Greater accuracy of results Arterial lactate levels represent total body lactate levels. Lactate with arterial blood gases are relevant for patients presenting with: hypoxia shock suspected sepsis mechanical ventilation

  10. Sepsis and Lactate

  11. Sepsis Lactate and the Surviving Sepsis Campaign

  12. Sepsis Lactate and the Surviving Sepsis Campaign

  13. B-Lac cassette Features and Benefits of the B-Lac cassette

  14. Overview Lactate Cassette Specifications Measures: pH, PO2, PCO2, tHb, SO2, and lactate Lactate range: 0.3 - 17.5 mmol/L (all others parameters are the same) Specimen: Whole blood only Storage: 2°C - 8°C Shelf life: 12 months Handling: Cassettes must be brought to room temperature for 1 hour prior to use. Usage: OPTI CCA-TS only. All serial numbers. Requires v3.0 software Controls: Uses OPTI Check controls

More Related