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Chromosomal Inheritance and Human Sex Determination

Chromosomal Inheritance and Human Sex Determination. Chromosomes!. Is this what Mendel would expect?. Is this what Mendel would expect?. Practice Question: Chromosomal Inheritance.

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Chromosomal Inheritance and Human Sex Determination

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  1. Chromosomal Inheritance and Human Sex Determination

  2. Chromosomes!

  3. Is this what Mendel would expect?

  4. Is this what Mendel would expect?

  5. Practice Question: Chromosomal Inheritance • If a color blind man has a child with a “wild-type” woman, what are the chances that this daughter of theirs will be colorblind? • What are the chances that their son will be colorblind? • Can females be colorblind? What would the genotype of the parents have to be?

  6. Human Sex Determination Textbook Story: XX = Female XY = Male With a few exceptions….

  7. Occasionally, chromosomes fail to sort correctly resulting in aneuploidy (unusual numbers of chromosomes)

  8. Aneuploidy can also occur with Sex Chromosomes XXY= Klinefelter Syndrome- phenotypically male with normal intelligence, sterile XO = Turner syndrome- phenotypically female, sterile, usually normal intelligence XYY = no general traits (tall) XXX = healthy, “normal”

  9. The SRY Gene

  10. Hormonal Signaling is Complex

  11. Hormone Production is Complex

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