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2008 년

2008 년. 미토콘드리아 유전체 연구팀 (mtDNA research lab). 정리 내용. 학술대회 참가및 연제발표 SCI 논문 논문발표 학술상 수상 연구과제 수행. 학술대회 참가 및 연제발표. 과기부 Stem Cell 연구사업단 발표 ( 김혜란 )/ 2008.01.25 ( 나주 중흥 골드스파 ) ‘ Mitochondrial Genetic Background Modifies Endothelial Progenitor Cells and

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2008 년

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  1. 2008년 미토콘드리아 유전체 연구팀 (mtDNA research lab)

  2. 정리 내용 • 학술대회 참가및 연제발표 • SCI논문 논문발표 • 학술상 수상 • 연구과제 수행

  3. 학술대회 참가 및 연제발표 • 과기부 Stem Cell 연구사업단 발표 (김혜란)/ 2008.01.25 (나주 중흥 골드스파) ‘Mitochondrial Genetic Background Modifies Endothelial Progenitor Cells and Hematopoietic Stem cells: Implication and Clinical Application’ • 2008년 대한진단검사의학회 춘계학술대회(신명근) • New Horizons in Hematology Meeting 참석 (독일/베를린)08.02.27 – 08.3.3 (신명근) ‘Remarkable allelic expression imbalance of JAK2 V617F mutant and phenotypic variation in BCR-ABL negative myeloproliferative neoplasms’ • 2008년 대한혈액학회 창립 50주년 기념 학술대회 08. 5.29-5.31(신명근, 김혜란) 5편 연제발표 • 유전및분자진단연구회 2008년 학술대회연제발표 08.7.2 (삼성서울병원)-신명근 ‘Mitochondrial DNA minisatellites as new markers for the quantitative determination of hematopoietic chimerism after allogeneic stem cell transplantation, • 2008년 대한 진단검사의학회 추계학술대회 08.10.20-21 5편 연제발표 • 2008년 미국혈액학회 50주년 기념 학술대회 08.12.06-09 ( 미국 샌프란시스코) 1편 초록 채택 ‘Discovery of a New Molecular Marker, Prohibitin, and Development of Candidates for New Chemotherapeutic Agents Targeting Prohibitin in Primary AML Cells’

  4. 2008 발표 SCI논문 –총 10편 발표 ★ 주저자 및 교신저자 1) Kim HR, Shin MG et al. Distribution of mitochondrial DNA haplogroups and phylogenetic characteristics in Korean population. Genes & Genomics 2008;30:121-126 2) Kim HR, Shin MG et al. Mitochondrial DNA Aberrations of Bone Marrow Cells from Patients with Aplastic Anemia. J KOREAN MED SCI 2008, under publication 3) Shin MG et al. Increased intestinal macromolecular permeability and urine nitrite excretion associated with liver cirrhosis with ascites. World Journal of Gastroenterology, 2008;14(24):3884-3890 4) Shin MG,et al. Tetrasomy 21 as a sole acquired abnormality without GATA1 gene mutation in pediatric acute megakaryoblastic leukemia: a case report and review of the literature.Leuk Res. 2008 Oct;32(10):1615-9. 5) Kim YK, Shin Mg, et al. Simultaneous occurrence of the JAK2V617F mutation and BCR-ABL gene rearrangement in patients with chronic myeloproliferative disorders.Leuk Res. 2008 Jun;32(6):993-5. 6) Kim JY, Shin MG, et al. Platelet factor-4 is an indicator of blood count recovery in acute myeloid leukemia patients in complete remission.Mol Cell Proteomics. 2008 Feb;7(2):431-41.

  5. ★ 공저자 7) Park JY, Shin MG, et al. In Vitro Amphotericin B Susceptibility of Korean Bloodstream Yeast Isolates Assessed by the CLSI Broth Microdilution Method, Etest, and Minimum Fungicidal Concentration Test. Korean J Lab Med. 2008 Oct;28:346-52. 8) Kim SH, Shin MG, et al. The relationship between antifungal usage and antifungal susceptibility in clinical isolates of Candida: a multicenter Korean study.Med Mycol. 2008 Jul 31:1-9. 9) Won Song J, Shin MG, et al. Expression of CgCDR1, CgCDR2, and CgERG11 in Candida glabrata biofilms formed by bloodstream isolates.Med Mycol. 2008 Jul 24:1-4. 10) Kim HN, Shin MG, et al. Association between folate-metabolizing pathway polymorphism and non-Hodgkin lymphoma.Br J Haematol. 2008 Feb;140(3):287-94. • ★ 투고논문 • Kim DW et al. Incidence and Causes of Eosinophilia from the Patients in a University Hospital. Kor J Lab Med (SCIE) 2008, submit to journal • Shin MG et al. Alteration of mitochondrial DNA sequence and copy number in nasal polyp tissue. Mitochondrion (SCI)) 2008. Under Review

  6. ★석사 및 박사 논문 (2009년 2월 졸업) ★ Manuscript preparation • Association of allelic expression imbalance of JAK2 V617F mutant and phenotypic diversity in BCR-ABL negative myeloproliferative neopla • Discovery of prohibitin as a new molecular marker and development of chemotherapeutic agents targeting prohibitin in primary acute myeloid leukemia cells(김혜란 박사) 2) 급성골수구성백혈병에서 백혈병줄기세포의 빈도 및 병리생태적 의의 (김명숙 석사) 3) 백혈병 미세잔존질환 정량검출을 위한 실시간 역전사중합효소연쇄반응법의 유용성(조정애 석사)

  7. 학술상 수상 • 2008년 BK 21 심포지움 (김혜란 우수포스터상 수상) • 2008. 5.29-5.31 신명근교수님 우수연구자상 수상 대한혈액학회 창립 50주년 기념 학술대회 ‘ Association of the prohibitin 3’ untranslated region polymorphisms with AML susceptibility’ • 2008. 5.29-5.31 김혜란 우수연제상 수상 대한혈액학회 창립 50주년 기념 학술대회 ‘ Prohibitin is highly expressed in primary AML cells: implications for  the loss of its pro-apoptotic function and  malignant growth, and new molecular target for treatment  of  AML’ • 2008년 대한진단검사의학회 춘계학술대회 (학회지 우수심사위원상)

  8. 5. 연구과제 수행 1) 단독연구과제 i) 08 과학재단 특정기초 선정(3년 과제 수행중) ii) 08 보건의료기술사업 과제 선정(2년 과제 수행중) 2) 세부연구과제 i) 과학재단 stem cell 연구 세부과제(수행중) ii) 바이오툴 특정 연구개발사업 위탁과제(08 수행중) iii) 환경성 질환연구센터 세부과제(08 수행중)

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