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Simulation of Light Ion Fragmentation Experiments Using GEANT4. Iwan Cornelius, Faiza Bourhaleb, Roberto Cirio, Flavio Marchetto. Torino INFN. Italian Heavy Ion Therapy Facility (CNAO) Development of beam monitoring hardware Treatment planning research Physics of ion interaction
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Simulation of Light Ion Fragmentation Experiments Using GEANT4 Iwan Cornelius, Faiza Bourhaleb, Roberto Cirio, Flavio Marchetto
Torino INFN • Italian Heavy Ion Therapy Facility (CNAO) • Development of beam monitoring hardware • Treatment planning research • Physics of ion interaction • Radiobiology
Fragmentation Models • Current TPS (ANCOD) requires fluence spectra of primary and secondaries with depth in patient f(Z,E,t)H2O • Information used with Radiobiological model to calculate equivalent dose • In past produced by GEANT3 w. FREESCO interface • Investigate models of fragmentation • Quantum Molecular Dynamics • JQMD + Interface to GEANT4 • GEANT 4.6.0 Includes binary cascade model
Model Verification • Simulate fragmentation experiments • Schall (GSI): Fragment yields (Z>4) for varying thickness water target • Matsufuji (NIRS): fragment yields (Z>1) for varying thickness PMMA target • Gunzert-Marx (GSI): fragment spectroscopy and angular dependence (n,p,d,t,He-3,a)
G4 Ion Physics • G4MultipleScattering • G4ionIonisation • G4HadronInelasticProcess • G4TripathiCrossSection • G4IonsShenCrossSection • G4BinaryLightIonReaction
Schall et.al. 1996 • Beam : C-12 676 AMeV • Target : H2O (variable thickness, t) • Detection system : Ionisation Chamber f(DE) • Information : N(Z,t) /No
Ionisation Chamber Target Beam Selection System Geometry
Gunzert-Marx et.al. 2003 • Beam : C-12 200 AMeV • Target : H2O (T>>R) • Detection system : Detector Telescope f(DE, E), TOF system • Information : N(q,E,X)
Start / IC Target Telescope q Geometry
To do • Simulate other data from Schall 1996 experiments with heavier ions O, N • Simulate Gunzert-Marx experiment • Simulate experiment of Matsufuji et.al. • Quantitative comparison using statistical packages?
Summary • Torino section INFN active in treatment planning system research for HIT • Investigating fragmentation model of GEANT4 • Comparison between TPS results using different models of ion fragmentation • Monte Carlo based treatment planning