Celeheal Capsules (Generic Celecoxib Capsules)

1. Celeheal Capsules (Generic Celecoxib Capsules) © Clearsky Pharmacy ( www.clearskypharmacy.biz )

2. Celeheal Capsules (Generic Celecoxib Capsules) Celeheal Capsules (Generic Celecoxib Capsules) belongs to the group of medicines called nonsteroidal anti- inflammatory drug (NSAID), which relieves pain and swelling (inflammation). Celeheal is used in the treatment of arthritis, acute pain, and menstrual pain and discomfort. The pain and swelling relief provided by this medication helps you perform more of your normal daily activities. Celecoxib Capsules work by blocking the enzyme in your body that makes prostaglandins. Decreasing prostaglandins helps to reduce pain and swelling. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

3. Celeheal Capsules (Generic Celecoxib Capsules) Active Ingredient The active ingredient present in Celeheal capsules is Celecoxib. Each Celeheal capsules contains 100 mg or 200 mg of Celecoxib. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

4. Celeheal Capsules (Generic Celecoxib Capsules) Chemical Structure The structure of Celecoxib is given below: © Clearsky Pharmacy ( www.clearskypharmacy.biz )

5. Celeheal Capsules (Generic Celecoxib Capsules) Celeheal Capsules are manufactured by Healing Pharma India Private Limited in the strength of 100 mg and 200 mg of Celecoxib. (Website: https://www.healingpharma.in/ ) URL: https://www.clearskypharmacy.biz/generic-celecoxib.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

6. Celeheal Capsules (Generic Celecoxib Capsules) Celecoxib Capsules – Brand Names Celecoxib capsules are available under various drug trade names that include Celebrex, Celeheal, Celebra, Onsenal, Cobix, Colcibra, Revibra, Celact, Celact-MD, Celcox, Celecap, Celedol, Celemax, Celetop, Celfast, Colcibra, Celib, Orthocel, Zecoxib, Zycel and Zycel MD. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

7. Celeheal Capsules (Generic Celecoxib Capsules) Uses of Celeheal Capsules Celeheal (Generic Celecoxib Capsules) is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain and help relieve symptoms of arthritis (eg, osteoarthritis, rheumatoid arthritis, or juvenile rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain. However, this medicine does not cure arthritis and will help you only as long as you continue to take it. Celeheal is also used to treat ankylosing spondylitis, which is a type of arthritis that affects the joints in the spine. This medicine may also be used to treat acute pain and menstrual cramps. Celeheal is also used to treat acute migraine headaches with or without aura. However, this medicine is not used to prevent migraines. URL: https://www.clearskypharmacy.biz/generic-celecoxib.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

8. Celeheal Capsules (Generic Celecoxib Capsules) Celeheal Capsules Dosage The dosage of Celeheal Capsules (Generic Celecoxib Capsules) is given below: Osteoarthritis: 200 mg once daily or 100 mg twice daily Rheumatoid Arthritis: 100 to 200 mg twice daily Juvenile Rheumatoid Arthritis: 50 mg twice daily in patients 10-25 kg. 100 mg twice daily in patients more than 25 kg Ankylosing Spondylitis: 200 mg once daily single dose or 100 mg twice daily. If no effect is observed after 6 weeks, a trial of 400 mg (single or divided doses) may be of benefit. Acute Pain and Primary Dysmenorrhea: 400 mg initially, followed by 200 mg dose if needed on first day. On subsequent days, 200 mg twice daily as needed. URL: https://www.clearskypharmacy.biz/generic-celecoxib.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

9. Celeheal Capsules (Generic Celecoxib Capsules) Celeheal Capsules Dosage The dosage of Celeheal Capsules (Generic Celecoxib Capsules) is given below: Familial Adenomatous Polyposis: 400 mg twice daily with food, as an adjunct to usual care. Reduce daily dose by 50% in patients with moderate hepatic impairment (Child-Pugh Class B). Consider a dose reduction by 50% (or alternative management for JRA) in patients who are known or suspected to be CYP2C9 poor metabolizers. URL: https://www.clearskypharmacy.biz/generic-celecoxib.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

10. Celeheal Capsules (Generic Celecoxib Capsules) Contraindications Celeheal Capsules are contraindicated in persons with a hypersensitivity (allergy) to Celecoxib or Sulfonamides or any of the other ingredients of this medicine. Celeheal (Celecoxib Capsules) must not be used in patients with a history of asthma, urticaria, or other allergic-type reactions after taking aspirin or any other NSAIDs. Use of Celeheal during the perioperative period in the setting of coronary artery bypass graft (CABG) surgery is also contraindicated. URL: https://www.clearskypharmacy.biz/generic-celecoxib.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

11. Celeheal Capsules (Generic Celecoxib Capsules) Storage Instructions Celeheal Capsules (Generic Celecoxib Capsules) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: https://www.clearskypharmacy.biz/generic-celecoxib.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

12. Celeheal Capsules (Generic Celecoxib Capsules) Warnings Serious and potentially fatal cardiovascular (CV) thrombotic events, myocardial infarction, and stroke. Patients with known CV disease/risk factors may be at greater risk. Serious gastrointestinal (GI) adverse events, which can be fatal. The risk is greater in patients with a prior history of ulcer disease or GI bleeding, and in patients at high risk for GI events, especially the elderly. Celeheal capsules should be used with caution in these patients. Elevated liver enzymes and, rarely, severe hepatic reactions. Discontinue use of Celeheal Capsules immediately if abnormal liver enzymes persist or worsen. New onset or worsening of hypertension. Blood pressure should be monitored closely during treatment with Celeheal Capsules. URL: https://www.clearskypharmacy.biz/generic-celecoxib.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

13. Celeheal Capsules (Generic Celecoxib Capsules) Warnings Fluid retention and edema. Celeheal Capsules should be used with caution in patients with fluid retention or heart failure. Renal papillary necrosis and other renal injury with long term use. Use Celeheal Capsules with caution in the elderly, those with impaired renal function, heart failure, liver dysfunction, and those taking diuretics, ACE-inhibitors, or angiotensin II antagonists. Anaphylactoid reactions. Do not use Celeheal Capsules in patients with the aspirin triad. Serious skin adverse events such as exfoliative dermatitis, Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal and can occur without warning even without known prior sulfa allergy. Discontinue Celeheal Capsules at first appearance of rash or skin reactions. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

14. Celeheal Capsules (Generic Celecoxib Capsules) Side Effects Most common Celecoxib (Celeheal capsules) side effects with an incidence rate of at least 2% and greater than placebo is abdominal pain, diarrhea, dyspepsia, flatulence, peripheral edema, accidental injury, dizziness, pharyngitis, rhinitis, sinusitis, upper respiratory tract infection, rash URL: https://www.clearskypharmacy.biz/generic-celecoxib.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

15. Celeheal Capsules (Generic Celecoxib Capsules) Overdose Doses of Celecoxib Capsules (Celeheal capsules) up to 2400 mg/day for up to 10 days administered to 12 patients did not result in serious toxicity. Symptoms following acute NSAID overdoses are usually limited to lethargy, drowsiness, nausea, vomiting, and epigastric pain, which are generally reversible with supportive care. Gastrointestinal bleeding can occur. Hypertension, acute renal failure, respiratory depression and coma can take place, but are rare. Anaphylactoid reactions have been observed with therapeutic ingestion of NSAIDs, and could occur following an overdose. URL: https://www.clearskypharmacy.biz/generic-celecoxib.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

16. Celeheal Capsules (Generic Celecoxib Capsules) Overdose Patients should be managed by symptomatic and supportive care following an Celeheal capsules overdose. Specific antidotes are not currently known. No information is available regarding the removal of Celecoxib by hemodialysis, but based on its high degree of plasma protein binding (greater than 97%) dialysis is not likely to be useful in overdose. Emesis and/or activated charcoal (60 to 100 g in adults, 1 to 2 g/kg in children) and/or osmotic cathartic can be prescribed to patients examined within 4 hours of ingestion with symptoms or following a large Celecoxib overdose. URL: https://www.clearskypharmacy.biz/generic-celecoxib.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

17. Celeheal Capsules (Generic Celecoxib Capsules) Celeheal Capsules During Pregnancy Celecoxib (Celeheal capsules) is classified by the US FDA as Pregnancy Category C (Pregnancy category D from 30 weeks of gestation onward). During animal studies, oral doses approximately 2-fold human exposure, caused an increased incidence of ventricular septal defects, a rare event, and fetal alterations, such as ribs fused, sternebrae fused and sternebrae misshapen when rabbits were treated throughout organogenesis. URL: https://www.clearskypharmacy.biz/generic-celecoxib.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

18. Celeheal Capsules (Generic Celecoxib Capsules) For more details on Celeheal Capsules click here Celeheal Capsules (Generic Celecoxib Capsules) by Healing Pharma India Private Limited. URL: https://www.clearskypharmacy.biz/generic-celecoxib.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )