Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets)

1. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) © Clearsky Pharmacy ( www.clearskypharmacy.biz )

2. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Ciplox (Generic Ciprofloxacin Hydrochloride Tablets) is a broad spectrum Fluoroquinolone antibacterial indicated in adults 18 years of age or more with the following infections caused by designated, susceptible bacteria and in pediatric patients where indicated: Skin and Skin Structure Infections, Bone and Joint Infections, Complicated Intra-Abdominal Infections, Infectious Diarrhea, Typhoid Fever (Enteric Fever), Uncomplicated Cervical and Urethral Gonorrhea, Inhalational Anthrax post-exposure in adult and pediatric patients, Plague in adult and pediatric patients, Chronic Bacterial Prostatitis, Lower Respiratory Tract Infections, Acute Exacerbation of Chronic Bronchitis, Urinary Tract Infections, Urinary Tract Infections (UTI), Acute Uncomplicated Cystitis, Complicated UTI and Pyelonephritis in Pediatric Patients and Acute Sinusitis. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

3. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Active Ingredient The active ingredient contained in ciplox tablets is Ciprofloxacin Hydrochloride. Each film-coated Ciplox tablet contains Ciprofloxacin Hydrochloride, IP equivalent to 250 mg or 500 mg Ciprofloxacin. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

4. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Chemical Structure The structure of Ciprofloxacin Hydrochloride is given below: © Clearsky Pharmacy ( www.clearskypharmacy.biz )

5. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Ciplox Tablets are manufactured by Cipla Limited, India in the strengths of 250 mg and 500 mg. (Website: www.cipla.com www.cipla.com) URL: URL: https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

6. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Ciprofloxacin Hydrochloride Tablets – Brand Names Ciprofloxacin Hydrochloride is available under various Drug trade names that include Cipro, Cipro XR, Proquin XR, Zoxan, Ciplox, Adiflox, Alcipro, Bekaycin and Biocip. URL: URL: https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

7. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Uses of Ciplox Tablets Ciplox (Generic Ciprofloxacin Hydrochloride Tablets) are used for the treatment of a wide variety of infections caused by susceptible gram- positive and gram-negative organisms, including mixed infections caused two or more organisms. It may also use for infections caused by multidrug- resistant bacteria. Ciprofloxacin is indicated for the treatment of the following infections caused by susceptible bacteria. Respiratory Tract Infections: Acute bronchitis, exacerbation of chronic obstructive airways disease, empyema, lung abscess, infected bronchiectasis, cystic fibrosis and pneumonia. Urinary Tract Infections (UTIs): Acute and chronic pyelonephritis, prostatitis, cystitis, epididymitis and chronic complicated or recurrent UTI caused by multi-resistant organisms and/or Pseudomonas aeruginosa. URL: URL: https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

8. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Uses of Ciplox Tablets Ciprofloxacin is indicated for the treatment of the following infections caused by susceptible bacteria. Skin and Soft Tissue Infections: In surgical and post-operative wound infections, due to gram-negative organisms such as Enterobacteriaceae and Pseudomonas aeruginosa. Also, useful in infections caused by resistant staphylococci. Surgical Infections: Peritonitis, intra-abdominal abscess, cholangitis, cholecystitis, empyema of gall bladder Bone and Joint infections: Since ciprofloxacin achieves adequate tissue concentrations in bone, it is useful in the management of acute and chronic osteomyelitis Gynecological Infections: Severe pelvic infections caused by susceptible bacteria URL: URL: https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

9. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Uses of Ciplox Tablets Ciprofloxacin is indicated for the treatment of the following infections caused by susceptible bacteria. Sexually Transmitted Diseases: Gonorrhea, including that caused y- beta-lactamase-producing strains. Chancroid caused by Haemophilus ducreyi. Gastrointestinal Infections: Effective in the treatment of typhoid and may also eradicate carrier stage. Useful in resistant Salmonella typhi infections. Severe Systemic Infections: Septicemia and bacteremia infections in immunocompromised patients. URL: URL: https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

10. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Ciplox Tablets Dosage Ciplox tablets (Generic Ciprofloxacin Hydrochloride Tablets) is given below: Ciplox tablets must be swallowed whole with adequate amount of liquid. Ciprofloxacin HCl tablets can be taken with or without regard to meals. Fluids should be taken liberally. Antacids should not be taken concomitantly or within two hours of dosing. The adult dosage for various indications is given below: Respiratory Tract, Bone And Joint Infections: Respiratory Tract, Bone And Joint Infections: Mild/moderate 500 mg twice daily/or 1000 mg once daily Severe/complicated 750 mg twice daily The dosage of Ciplox tablets URL: URL: https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

11. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Ciplox Tablets Dosage Ciplox tablets (Generic Ciprofloxacin Hydrochloride Tablets) is given below: Urinary Tract Infections Urinary Tract Infections Acute uncomplicated 500 mg once daily for 3 days Mild/moderate 250 mg twice daily / 500 mg once daily Severe/complicated 500 mg twice daily/or 1000 mg once daily Infectious Diarrhoea Infectious Diarrhoea Mild/moderate/severe 500 mg twice daily/or 1000 mg once daily Gonorrhoea: Gonorrhoea: 250 mg single dose Non-Gonococcal Urethritis: Non-Gonococcal Urethritis: 750 mg twice daily Chancroid: Chancroid: 500 mg twice daily/1000 mg once daily Other infections: Other infections: 500 to 750 mg twice daily Chronic Bacterial prostatitis: Chronic Bacterial prostatitis: 1000 mg once daily for 28 days The dosage of Ciplox tablets © Clearsky Pharmacy ( www.clearskypharmacy.biz )

12. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Contraindications Ciplox tablets are contraindicated in patients with a hypersensitivity to Ciprofloxacin Hydrochloride, other quinolones or any other component of this medication. Concomitant administration with Tizanidine is contraindicated. This medicine is not recommended in children below the age of 18 years. URL: URL: https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

13. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Storage Instructions Ciplox (Generic Ciprofloxacin Hydrochloride Tablets) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: URL: https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

14. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Warnings Hypersensitivity and other serious reactions: Serious and sometimes fatal reactions (for example, anaphylactic reactions) may occur after the first or subsequent doses of Ciplox tablets. Discontinue Ciplox at the first sign of skin rash, jaundice or any sign of hypersensitivity. Hepatotoxicity: Discontinue immediately if signs and symptoms of hepatitis occur. Clostridioides difficile-associated diarrhea: Evaluate if colitis occurs. QT Prolongation: Prolongation of the QT interval and isolated cases of torsade de pointes have been reported. Avoid use in patients with known prolongation, those with hypokalemia, and with other drugs that prolong the QT interval. URL: URL: https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

15. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Ciplox Tablets and Alcohol Taking Ciplox tablets with alcohol will not make the antibiotic less effective, but the combination might increase the risk of certain side effects or make side effects worse. Examples of side effects that might be more likely to occur, or worsened by alcohol use, include: nausea, vomiting, dizziness, upset stomach, liver problems URL: URL: https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

16. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Side Effects Ciplox tablets (Ciprofloxacin) are generally well tolerated. The common side effects of Ciprofloxacin with an incidence rate of 15 or more are nausea, diarrhea, liver function tests abnormal, vomiting, and rash. Other side effects which have been reported include abdominal pain, headache, restlessness, myalgia, tendonitis/rupture, exacerbation of myasthenia gravis and increases in serum transaminase levels. URL: URL: https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

17. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Ciplox Tablets Overdose In the event of acute Ciplox tablets overdosage, reversible renal toxicity has been reported in some cases. Empty the stomach by inducing vomiting or by gastric lavage. Observe the patient carefully and give supportive treatment, including monitoring of renal function, urinary pH and acidify, if required, to prevent crystalluria and administration of magnesium, aluminum, or calcium containing antacids which can reduce the absorption of Ciprofloxacin. Adequate hydration must be maintained. Only a small amount of Ciprofloxacin (less than 10%) is removed from the body after hemodialysis or peritoneal dialysis. URL: URL: https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

18. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Ciplox Tablets During Pregnancy Ciprofloxacin Hydrochloride (Ciplox Tablets) has been classified by the US FDA as Pregnancy Category C. There are no adequate and well-controlled studies conducted in pregnant women. Ciprofloxacin Hydrochloride tablets (Ciplox Tablets) must not be used during pregnancy unless the potential benefit justifies the potential risk to both fetus and mother. An expert review of published data on experiences with Ciprofloxacin use during pregnancy by TERIS–the Teratogen Information System– concluded that therapeutic doses during pregnancy are unlikely to pose a substantial teratogenic risk (quantity and quality of data=fair), but the data are insufficient to state that there is no risk. URL: URL: https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

19. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Ciplox Tablets During Nursing Ciprofloxacin (Ciplox tablets) is excreted in human milk. The amount of ciprofloxacin absorbed by the nursing infant is unknown. Because of the potential risk of serious adverse reactions (including articular damage) in infants nursing from mothers taking Ciplox tablets, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. URL: URL: https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

20. Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets) Ciplox Tablets Ciplox Tablets (Generic Ciprofloxacin Hydrochloride Tablets) are manufactured by Cipla Limited, India. URL: URL: https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html https://www.clearskypharmacy.biz/generic-cipro-zoxan-by-fdc.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )