Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets)

1. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) © Clearsky Pharmacy ( www.clearskypharmacy.biz )

2. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) is a combination containing Tadalafil 20mg and Dapoxetine 60mg in a single tablet. Generic Tadalafil and Dapoxetine Tablets are used for the treatment of male erectile dysfunction as well as treatment of premature ejaculation in men at the same time. Tadalafil is used to treat men who have erectile dysfunction (also called sexual impotence). Dapoxetine Hydrochloride is used to treat premature ejaculation in adult men aged 18 to 64 years. Dapoxetine increases the time it takes to ejaculate and can improve the control over the ejaculation. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

3. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Active Ingredient The active ingredients contained in Super Vidalista tablets are Tadalafil and Dapoxetine Hydrochloride. Each Tadalafil Dapoxetine combination tablet contains 20 mg of Tadalafil and 60 mg of Dapoxetine. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

4. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Chemical Structure The structure of Tadalafil is given below: © Clearsky Pharmacy ( www.clearskypharmacy.biz )

5. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Chemical Structure The structure of Dapoxetine Hydrochloride is given below: © Clearsky Pharmacy ( www.clearskypharmacy.biz )

6. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Super Vidalista Tablets are manufactured by Centurion Remedies Private Limited, India in the strength of 80 mg (20 mg of Tadalafil and 60 mg of Dapoxetine Hydrochloride). (Website: https://www.centurionremedies.com/ ) URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

7. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Tadalafil Dapoxetine Tablets – Brand Names Tadalafil Dapoxetine combination tablets tablets are available as Tadali Superb Tablets, Duraplus Tablets, Super Vidalista Tablets, Super Tadalista Tablets, Super Tadalis SX Tablets and Super Tadarise Tablets. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

8. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Uses of Super Vidalista Tablets Super Vidalista (Generic Tadalafil and Dapoxetine Tablets) is a Combination medication containing Tadalafil 20mg and Dapoxetine 60mg in a single tablet. Tadalafil Dapoxetine Tablets are used for the treatment of male erectile dysfunction as well as treatment of premature ejaculation in men at the same time. Tadalafil is used to treat men who have erectile dysfunction (also called sexual impotence). These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. By controlling the enzyme, Tadalafil helps to maintain an erection after the penis is stroked by increasing blood flow to the penis. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

9. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Uses of Super Vidalista Tablets Dapoxetine Hydrochloride is used to treat premature ejaculation in adult men aged 18 to 64 years. Dapoxetine increases the time it takes to ejaculate and can improve the control over the ejaculation. Dapoxetine is indicated for the treatment of premature ejaculation (PE) in men 18 to 64 years of age, who have all of the following: persistent or recurrent ejaculation with minimal sexual stimulation before, on, or shortly after penetration and before the patient wishes; and marked personal distress or interpersonal difficulty as a consequence of PE; and poor control over ejaculation. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

10. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Super Vidalista Tablets Dosage The dosage of Super Vidalista tablets (Generic Tadalafil and Dapoxetine Tablets) is given below: The dose of Super Vidalista tablets is orally one tablet once a day, with or without meals. The tablet has to be administered one to three hours before sexual activity. Do not take more than 1 tablet in any 24 hour period. i.e. At least 24 hours should pass before you take the next dose. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

11. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Contraindications Super Vidalista tablets are contraindicated in patients with a known hypersensitivity to Tadalafil, Dapoxetine Hydrochloride or any other component of the tablet. Administration of this medicine to patients using any form of organic nitrate is contraindicated. Tadalafil was shown to potentiate the hypotensive effect of nitrates. Administration of this medicine to patients with significant pathological cardiac conditions is contraindicated. A history of mania or severe depression. Concomitant treatment with Thioridazine, or within 14 days of discontinuing treatment with Thioridazine. Similarly, Thioridazine should not be administered within 7 days after Super Vidalista tablets have been discontinued. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

12. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Contraindications Concomitant treatment with serotonin reuptake inhibitors [selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs)] or other medicinal/herbal products with serotonergic effects [e.g., L-Tryptophan, Triptans, Tramadol, Linezolid, Lithium, St. John's Wort (Hypericum perforatum)] or within 14 days of discontinuing treatment with these medicinal/herbal products. Similarly, these medicinal/herbal products should not be administered within 7 days after this medicine has been discontinued. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

13. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Contraindications Concomitant treatment of potent CYP3A4 inhibitors such as Ketoconazole, Itraconazole, Ritonavir, Saquinavir, Telithromycin, Nefazadone, Nelfinavir, Atazanavir, etc. is contraindicated. Moderate and severe hepatic impairment. Do not use Super Vidalista tablets in patients who are using a GC stimulator, such as Riociguat. Tadalafil may potentiate the hypotensive effects of GC stimulators. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

14. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Storage Instructions Super Vidalista (Generic Tadalafil and Dapoxetine Tablets) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

15. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Warnings Patients should not use Super Vidalista tablets if sex is inadvisable due to cardiovascular status. Use of Super Vidalista tablets with alpha blockers, antihypertensives or substantial amounts of alcohol (5 units or greater) may lead to hypotension. This medicine is not recommended in combination with alpha blockers for the treatment of BPH because efficacy of the combination has not been adequately studied and because of the risk of blood pressure lowering. Caution is advised when Tadalafil Dapoxetine tablets are used as a treatment for ED in men taking alpha blockers. Super Vidalista tablets are not suitable and should not be used if taking potent inhibitors of CYP3A4. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

16. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Warnings Patients should seek emergency treatment if an erection lasts for more than 4 hours. Use Super Vidalista tablets with caution in patients predisposed to priapism. Patients should stop Super Vidalista tablets and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of Non Arteritic Ischemic Optic Neuropathy (NAION). Discuss increased risk of NAION in patients with history of NAION. Patients should stop Tadalafil and Dapoxetine tablets and seek prompt medical attention in the event of sudden decrease or loss of hearing. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

17. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Warnings Dapoxetine, a constituent of Super Vidalista is only indicated in men with Premature Ejaculation who meet all the criteria listed listed earlier. Dapoxetine should not be prescribed to men who have not been diagnosed with Premature Ejaculation. Safety has not been established and there are no data on the ejaculation-delaying effects in men without Premature Ejaculation. Before treatment initiation, a careful medical examination including history of orthostatic events should be performed by the physician. An orthostatic test should be performed before initiating therapy (blood pressure and pulse rate, supine and standing). In case of a history of documented or suspected orthostatic reaction, treatment with Super Vidalista tablets should be avoided. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

18. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Warnings Antidepressants, including SSRIs, increased the risk compared to placebo of suicidal thinking and suicidality in short-term studies in children and adolescents with Major Depressive Disorder and other psychiatric disorders. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24. In clinical trials with Dapoxetine, a constituent of Tadalafil Dapoxetine tablets for the treatment of premature ejaculation, there was no clear indication of treatment-emergent suicidality in evaluation of possibly suicide-related adverse events. Patients should avoid operating hazardous machinery, should syncope or its prodromal symptoms such as dizziness or lightheadedness occur. The risk of adverse cardiovascular outcomes from syncope (cardiac syncope and syncope from other causes) is increased in patients with underlying structural cardiovascular disease. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

19. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Warnings Patients should be advised not to use Super Vidalista tablets in combination with recreational drugs. Patients should be advised not to use Tadalafil and Dapoxetine tablets in combination with alcohol. Combining alcohol with dapoxetine may increase alcohol-related neurocognitive effects and may also enhance neurocardiogenic adverse events such as syncope, thereby increasing the risk of accidental injury; therefore, patients should be advised to avoid alcohol while taking Super Vidalista tablets . Tadalafil and Dapoxetine tablets should be prescribed with caution in patients taking medicinal products with vasodilatation properties (such as alpha adrenergic receptor antagonists and nitrates) due to possible reduced orthostatic tolerance. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

20. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Warnings This medicine is not suitable in patients taking moderate CYP3A4 inhibitors and in patients taking potent CYP2D6 inhibitors since the Dapoxetine dose is restricted to 30 mg. Super Vidalista tablets should not be used in patients with a history of mania/hypomania or bipolar disorder and should be discontinued in any patient who develops symptoms of these disorders. Due to the potential of SSRIs to lower the seizure threshold, Tadalafil Dapoxetine tablets should be discontinued in any patient who develops seizures and avoided in patients with unstable epilepsy. Patients with controlled epilepsy should be carefully monitored. Super Vidalista tablets should not be used in individuals below 18 years of age. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

21. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Warnings Super Vidalista tablets are not indicated for psychiatric disorders and should not be used in men with these disorders, such as schizophrenia, or in those suffering with co-morbid depression, as worsening of symptoms associated with depression cannot be excluded. There have been reports of bleeding abnormalities with SSRIs. Caution is advised in patients taking this medicine, particularly in concomitant use with medicinal products known to affect platelet function or anticoagulants, as well as in patients with a history of bleeding or coagulation disorders. Super Vidalista tablets are not recommended for use in patients with severe renal impairment and caution is advised in patients with mild or moderate renal impairment. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

22. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Warnings Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this Tadalafil Dapoxetine tablets. The use of Dapoxetine, a constituent of Tadalafil Dapoxetine tablets has been associated with ocular effects such as mydriasis and eye pain. Dapoxetine should be used with caution in patients with raised intraocular pressure or those at risk of angle closure glaucoma. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

23. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Withdrawal Effects Abrupt discontinuation of chronically administered SSRIs used to treat chronic depressive disorders has been reported to result in the following symptoms: dysphoric mood, irritability, agitation, dizziness, sensory disturbances (e.g., paresthesias such as electric shock sensations), anxiety, confusion, headache, lethargy, emotional lability, insomnia and hypomania. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

24. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Side Effects Most common side effects of Super Vidalista (Generic Tadalafil and Dapoxetine Tablets) are increased thirst and a light-headedness following sudden movements - this is natural, as blood moves into the genital areas. The common side effects include headache, dyspepsia, back pain, myalgia, nasal congestion, flushing, nausea, dizziness, diarrhoea, insomnia,fatigue and pain in limb. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

25. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Overdose Single doses up to 500 mg of Tadalafil have been given to healthy subjects, and multiple daily doses up to 100 mg have been given to patients. Adverse events were similar to those seen at lower doses. In cases of overdose, standard supportive measures should be adopted as required. Hemodialysis contributes negligibly to Tadalafil elimination. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

26. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Overdose No case of Dapoxetine overdose has been reported. There were no unexpected adverse events in a clinical pharmacology study of Dapoxetine with daily doses up to 240 mg (two 120 mg doses given 3 hours apart). In general, symptoms of overdose with SSRIs include serotonin-mediated adverse reactions such as somnolence, gastrointestinal disturbances such as nausea and vomiting, tachycardia, tremor, agitation and dizziness. In cases of overdose, standard supportive measures should be adopted as required. Due to high protein binding and large volume of distribution of Dapoxetine Hydrochloride, forced diuresis, dialysis, hemoperfusion and exchange transfusion are unlikely to be of benefit. No specific antidotes for Dapoxetine are known. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

27. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) Super Vidalista Tablets During Pregnancy Super Vidalista is a combination medication containing Tadalafil and Dapoxetine Hydrochloride. Tadalafil has been classified by the US FDA as Pregnancy Category B. Dapoxetine Hydrochloride has been classified by the US FDA as Pregnancy Category C. Super Vidalista tablets are not indicated for use by women. There is no evidence to suggest that Dapoxetine Hydrochloride exposure has an effect on a partner's pregnancy based on limited observational data obtained from the clinical trial database. There are no adequate and well-controlled studies of Tadalafil or Dapoxetine conducted in pregnant women. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

28. Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) For more details on Super Vidalista Tablets click here Super Vidalista Tablets (Generic Tadalafil and Dapoxetine Tablets) by Centurion Remedies Private Limited, India. URL: https://www.clearskypharmacy.biz/tadalafil-and-dapoxetine-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )