Tadali Tablets (Generic Tadalafil Tablets)

1. Tadali Tablets (Generic Tadalafil Tablets) © Clearsky Pharmacy ( www.clearskypharmacy.biz )

2. Tadali Tablets (Generic Tadalafil Tablets) Tadali (Generic Tadalafil Tablets) is a PDE5 inhibitor prescribed for the treatment of erectile dysfunction (ED), also known as impotence, in men 18 years and above. Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. It is also approved by the US FDA for treating the signs and symptoms of benign prostatic hyperplasia (BPH) as well as a combination of BPH and erectile dysfunction when the conditions coincide. This medicine is also used for the treatment of pulmonary arterial hypertension. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

3. Tadali Tablets (Generic Tadalafil Tablets) Active Ingredient The active ingredient present in Tadali tablets is Tadalafil. Each tablet contains 20 mg of Tadalafil. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

4. Tadali Tablets (Generic Tadalafil Tablets) Chemical Structure The structure of Tadalafil is given below: © Clearsky Pharmacy ( www.clearskypharmacy.biz )

5. Tadali Tablets (Generic Tadalafil Tablets) Tadali tablets, manufactured by Alpha-Pharma Healthcare Private Limited, India are available in the strength of 20mg. ( Website: https://www.alpha-pharma.com/ ) URL: https://www.clearskypharmacy.biz/generic-tadalafil-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

6. Tadali Tablets (Generic Tadalafil Tablets) Tadalafil Tablets – Brand Names Tadalafil tablets are available under various drug trade names that include Tadali, Tadalista, Tadacip, Tadalift, Cialis, Adcirca, Filda, Forzest, Megalis, Tadalis, Tazzle, Zydalis. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

7. Tadali Tablets (Generic Tadalafil Tablets) Uses of Tadali Tablets Tadali (Generic Tadalafil Tablets) is used to treat men who have erectile dysfunction (also called sexual impotence). Tadalafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works. Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. When a man is sexually stimulated, his body's normal response is to increase blood flow to his penis to produce an erection. By controlling the enzyme, tadalafil helps to maintain an erection after the penis is stroked by increasing blood flow to the penis. Without physical action to the penis, such as that occurring during sexual intercourse, Tadalafil will not work to cause an erection. URL: https://www.clearskypharmacy.biz/generic-tadalafil-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

8. Tadali Tablets (Generic Tadalafil Tablets) Uses of Tadali Tablets Tadalafil is also used to treat men who have signs and symptoms of benign prostatic hyperplasia (BPH). BPH is caused by an enlarged prostate. This medicine is also used to treat erectile dysfunction and signs and symptoms of BPH. Tadalafil is also used in both men and women to treat the symptoms of pulmonary arterial hypertension to improve your ability to exercise. This is high blood pressure that occurs in the main artery that carries blood from the right side of the heart (the ventricle) to the lungs. URL: https://www.clearskypharmacy.biz/generic-tadalafil-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

9. Tadali Tablets (Generic Tadalafil Tablets) Tadali Tablets Dosage The dosage of Tadali tablets (Generic Tadalafil Tablets) is given below: Tadali for use as needed: Erectile dysfunction (ED): Starting dose: 10 mg as needed prior to sexual activity. Increase to 20 mg or decrease to 5 mg based upon efficacy/tolerability. Improves erectile function compared to placebo up to 36 hours post dose. Not to be taken more than once per day. URL: https://www.clearskypharmacy.biz/generic-tadalafil-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

10. Tadali Tablets (Generic Tadalafil Tablets) Tadali Tablets Dosage The dosage of Tadali tablets (Generic Tadalafil Tablets) is given below: Tadali for once daily use: ED: 2.5 mg taken once daily, without regard to timing of sexual activity. May increase to 5 mg based upon efficacy and tolerability. Benign Prostatic Hyperplasia (BPH): 5 mg, taken at approximately the same time every day. ED and BPH: 5 mg, taken at approximately the same time every day. URL: https://www.clearskypharmacy.biz/generic-tadalafil-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

11. Tadali Tablets (Generic Tadalafil Tablets) Contraindications Tadali is contraindicated in patients with a hypersensitivity to Tadalafil or any other component of this medication. Administration of Tadali (Tadalafil Tablets) to patients using any form of organic nitrate is contraindicated. Tadali was shown to potentiate the hypotensive effect of nitrates. Tadali tablets, must not be used in men with cardiac disease for whom sexual activity is inadvisable. Physicians should consider the potential cardiac risk of sexual activity in patients with pre-existing cardiovascular disease. URL: https://www.clearskypharmacy.biz/generic-tadalafil-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

12. Tadali Tablets (Generic Tadalafil Tablets) Contraindications Tadali tablets are contraindicated in patients who have loss of vision in one eye because of non-arteritic anterior ischaemic optic neuropathy (NAION), regardless of whether this episode was in connection or not with previous PDE5 inhibitor exposure. The co-administration of PDE5 inhibitors, including Tadalafil tablets(Tadali), with guanylate cyclase stimulators, such as Riociguat, is contraindicated as it may potentially lead to symptomatic hypotension. URL: https://www.clearskypharmacy.biz/generic-tadalafil-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

13. Tadali Tablets (Generic Tadalafil Tablets) Storage Instructions Tadali Tablets (Generic Tadalafil Tablets) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: https://www.clearskypharmacy.biz/generic-tadalafil-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

14. Tadali Tablets (Generic Tadalafil Tablets) Warnings Patients should not use Tadali tablets if sex is inadvisable due to cardiovascular status. Use of Tadali tablets with alpha-blockers, antihypertensives or substantial amounts of alcohol (greater than 5 units) may lead to hypotension. Tadali tablets are not recommended in combination with alpha-blockers for the treatment of BPH because efficacy of the combination has not been adequately studied and because of the risk of blood pressure lowering. Caution is advised when Tadali is used as a treatment for ED in men taking alpha-blockers. Patients should seek emergency treatment if an erection lasts for greater than 4 hours. Use Tadali tablets with caution in patients predisposed to priapism. URL: https://www.clearskypharmacy.biz/generic-tadalafil-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

15. Tadali Tablets (Generic Tadalafil Tablets) Warnings Patients should stop Tadali tablets and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of non-arteritic anterior ischemic optic neuropathy (NAION). Tadali tablets must be used with caution, and only when the anticipated benefits outweigh the risks, in patients with a history of NAION. Patients with a "crowded" optic disc may also be at an increased risk of NAION. Patients should stop Tadali tablets and seek prompt medical attention in the event of sudden decrease or loss of hearing. Prior to initiating treatment with Tadali tablets for Benign Prostatic Hyperplasia (BPH), consideration should be given to other urological conditions that may cause similar symptoms. URL: https://www.clearskypharmacy.biz/generic-tadalafil-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

16. Tadali Tablets (Generic Tadalafil Tablets) Side Effects Most common Tadalafil (Tadali tablets) side effects with an incidence rate of 2% or more include headache, dyspepsia, back pain, myalgia, nasal congestion, flushing, and pain in limb URL: https://www.clearskypharmacy.biz/generic-tadalafil-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

17. Tadali Tablets (Generic Tadalafil Tablets) Side Effects The following side effects occurred with a frequency of less than 2% in controlled clinical trials of Tadalafil tablets for once daily use or use as needed. : Body as a Whole - asthenia, face edema, fatigue, pain Cardiovascular - angina pectoris, chest pain, hypotension, myocardial infarction, postural hypotension, palpitations, syncope, tachycardia Digestive - abnormal liver function tests, dry mouth, dysphagia, esophagitis, gastritis, GGTP increased, loose stools, nausea,upper abdominal pain, vomiting, gastroesophageal reflux disease, hemorrhoidal hemorrhage, rectal hemorrhage Musculoskeletal - arthralgia, neck pain Nervous - dizziness, hypesthesia, insomnia, paresthesia, somnolence, vertigo URL: https://www.clearskypharmacy.biz/generic-tadalafil-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

18. Tadali Tablets (Generic Tadalafil Tablets) Side Effects The following side effects occurred with a frequency of less than 2% in controlled clinical trials of Tadalafil tablets for once daily use or use as needed. : Renal and Urinary - renal impairment Respiratory - dyspnea, epistaxis, pharyngitis Skin and Appendages - pruritus, rash, sweating Ophthalmologic - blurred vision, changes in color vision, conjunctivitis (including conjunctival hyperemia), eye pain, lacrimation increase, swelling of eyelids Otologic - sudden decrease or loss of hearing, tinnitus Urogenital - erection increased, spontaneous penile erection URL: https://www.clearskypharmacy.biz/generic-tadalafil-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

19. Tadali Tablets (Generic Tadalafil Tablets) Overdose Single doses of Tadalafil (Tadali Tablets) up to 500 mg have been given to healthy subjects, and multiple daily doses up to 100 mg have been given to patients. Adverse events were similar to those seen at lower doses. In cases of Tadalafil overdose, standard supportive measures must be adopted as required. Hemodialysis contributes negligibly to Tadalafil elimination. URL: https://www.clearskypharmacy.biz/generic-tadalafil-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

20. Tadali Tablets (Generic Tadalafil Tablets) Tadali Tablets During Pregnancy Tadalafil (Tadali tablets) is classified by the US FDA as Pregnancy Category B. Tadalafil (Tadali tablets) is not indicated for use in women. There are no adequate and well controlled studies of Tadalafil tablets use in pregnant women. Animal studies do not indicate direct or indirect harmful effects with respect to pregnancy, embryonal / foetal development, parturition or postnatal development. Animal reproduction studies showed no evidence of teratogenicity, embryotoxicity, or fetotoxicity when Tadalafil was given to pregnant rats or mice at exposures up to 11 times the maximum recommended human dose (MRHD) of 20 mg/day during organogenesis. URL: https://www.clearskypharmacy.biz/generic-tadalafil-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

21. Tadali Tablets (Generic Tadalafil Tablets) For more details on Tadali Tablets click here Tadali (Generic Tadalafil Tablets) by Alpha Pharma Healthcare Private limited, India. URL: https://www.clearskypharmacy.biz/generic-tadalafil-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )