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Perioperative Care. Kimberly Ephgrave, MD, FACS Professor of Surgery University of Iowa Carver College of Medicine. Ms. Sedentary. Your patient is a 63 y/o woman who needs an elective subtotal colectomy.
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Perioperative Care Kimberly Ephgrave, MD, FACS Professor of Surgery University of Iowa Carver College of Medicine
Ms. Sedentary • Your patient is a 63 y/o woman who needs an elective subtotal colectomy. • She has multiple lesions in right, left, and transverse colon but no invasion on biopsies. • You agree that it is not urgent, and it would be wise to optimize her health status.
History • What co-morbid conditions affect surgical risk? • Which can be altered if we are willing to delay surgery a few months?
Risk Factors that Might be Changed • Malnutrition: Decreases wound healing, increases infectious complications • Chronic obstructive lung disease: Pulmonary complications • Current Smoking: Wound complications. • Hyperglycemia: Sepsis and mortality in ICU’s • Coronary Artery Disease: Cardiac morbidity
Risk Factors I: Ms. Sedentary • Malnutrition not present: Ms. Sedentary has an albumin of 4.5 and pre-albumin of 30; she is obese. • Chronic obstructive lung disease: She has a ‘smoker’s cough’ productive of colored sputum. • Smoking status: Ms. Sedentary smokes about 1 ppd, down from a peak of > 2 ppd.
Risk Factors II: Ms. Sedentary • Hyperglycemia: Ms. Sedentary is an obese diabetic, on two oral medications, with a hemoglobin A 1C of 7.8%. • Coronary Artery Disease: Ms. Sedentary is hypertensive. She does not have angina, but her ability to exercise is limited by claudication.
Physical Exam What would you look for?
Physical Exam • BMI 32 • Diminished pedal pulses • Harsh upper airway noises; clear with cough • Afebrile, BP 154/88, HR 84 and regular with no murmurs or gallops
What should be done about smoking? • Early papers suggested recent cessation worse than no cessation. • Recent studies: Lower wound and pulmonary complications if cessation for > 3-4 weeks. • Elective cosmetic surgery probably not indicated in current smokers due to doubling wound healing complication rates. • Close follow-up and bupropion both helpful.
What about ‘smoker’s cough’? • Rule out pneumonia • Treat active bronchitis with antibiotics. • Treat bronchospasm with bronchodilators. • Add steroids if needed for persistent bronchospasm.
What about a cardiac workup? • Good studies of non-cardiac surgery in patients with peripheral vascular disease suggest invasive testing not indicated in the absence of symptoms. • However, beta blockade IS indicated perioperatively. • Titrate to HR < 70 as long as BP is not hypotensive.
Who qualifies for beta-blockade? • Two or more of the following risk factors: • Age > 65 • Hypertension • Current smoker • Hypercholesterolemia • Diabetes
Pre-Operative Course:You successfully treat her bronchitis, begin bronchodilators, and help her to quit smoking pre-operatively. You also place her on atenolol, and maintain a heart rate less than 70 peri-operatively. What should you do Next ?
Pre-op prophylaxis • Bowel Prep ? • DVT ? • Antibiotic ?
ICU Studies • Normoglycemia: Less mortality, less sepsis • Insulin administration: No protective effect per se.
Sliding Scale vs. Insulin drip • Sliding scales generally allow more time spent in higher (> 200) ranges. • Insulin drip potentially more dangerous outside of ICU’s because staffing may be low and checks for hypoglycemia infrequent. • Blood sugars above 150-200 range interfere with white blood cell function, affecting wound healing and resistance to infection.
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