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Pedigree Notes

Discover how pedigrees track traits within family lines to determine inheritance methods, particularly for diseases. Explore autosomal dominant, autosomal recessive, and sex-linked inheritance, alongside examples like hemophilia and Huntington's disease.

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Pedigree Notes

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  1. Pedigree Notes

  2. What are pedigrees? • Pedigrees track traits within lines of descent (family trees) and are used to figure out the method of inheritance of certain traits (usually diseases)

  3. Methods of inheritance • Autosomal dominant: dominant trait carried on chromosomes in pairs 1-22 • Autosomal recessive: recessive trait carried on chromosomes in pairs 1-22 • Sex linked: carried on X or Y chromosome (can be dominant or recessive)

  4. Examples • Y linked • Y chromosome infertility • X linked Recessive: • Hemophilia • X linked Dominant: • Fragile X Syndrome • Autosomal Recessive: • Cystic Fibrosis • Sickle Cell Anemia • Autosomal Dominant: • Huntington’s Disease • Marfan Syndrome

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