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The Top 20 Drugs Your Dental Patient is Taking: Drug Interactions and Oral Manifestations

The Top 20 Drugs Your Dental Patient is Taking: Drug Interactions and Oral Manifestations. Ronald S. Brown, DDS, MS. The Top Twenty Prescriptions. Rxlist.com/top200.htm 2002 drugs New & Refill. #1, #1 - #4 Hydroxycodone/APAP #3. Oral narcotic analgesic abuse potential.

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The Top 20 Drugs Your Dental Patient is Taking: Drug Interactions and Oral Manifestations

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  1. The Top 20 Drugs Your Dental Patient is Taking: Drug Interactions and Oral Manifestations Ronald S. Brown, DDS, MS

  2. The Top Twenty Prescriptions Rxlist.com/top200.htm 2002 drugs New & Refill

  3. #1, #1 - #4 Hydroxycodone/APAP #3 • Oral narcotic analgesic • abuse potential

  4. #2, #2 - #8 Lipitor #62 • atorvastatin • cholesterol lowering agent

  5. #3 Atenalol, #4, #5 • Previous brand name Tenormin • Beta blocker – selective B1 • Negative on lipid profile

  6. #4, #5, #4 - #2 Synthroid #3 • Levothyroxine Na • Thyroxin replacement drug

  7. #5, #3, #3 - #2 Premarin #1 • Conjugated estrogen • hormone replacement • breast and ovarian cancer vs. osteoporosis

  8. #6, #7, #19 - #7 Zithromax #9 • Azithromycin • antibiotic • new generation erythromycin • less drug interactions

  9. #7, #8 Furosemide • Furosemide • Diuretic (very potent) • Dry mouth

  10. #8, #9, #14 - #15 Amoxicillin #33 • Broad spectrum antibiotic • Good penetration • Gram positive organisms

  11. #9, #10, #9 - #9 Norvasc #10 • Amlodipine besylate • Long-acting calcium channel blocking agent • drug-induced gingival overgrowth/hyperplasia

  12. #10, #14, #17 Hydrochlorothiazide • HCTZ • Diuretic • Decreases lipid profile • K+ loss • Dry mouth

  13. #11, #11, #10 Alprazolam • Alprazolam/Xanax (one of the brand names) • Sedative-hypnotic • Benzodiazepine class of drugs • Anti-anxiety

  14. #12, #12, #8 - #13 Albuterol Aerosol #18 • Albuterol (Ventolin) • B2 receptor agonist • Asthma medication

  15. #13, #16, #18 - #12 Zoloft #11 • Sertraline • 5HT re-uptake inhibitor • Dry mouth

  16. #14, #17 Paxil • Paroxetine • 5HT reuptake inhibitor • Antidepressant • Dry mouth

  17. #15, Zocor • Simvastatin • Cholesterol lowering

  18. #16, Prevacid • Lansoprazole • H1 blocker • GERD

  19. #17, #20, #21 Ibuprofen • NSAID • Analgesic, antipyretic • GI problems, ulcers • Increased bleeding • Drug interactions • Asthma

  20. #18, #18 Triamterene/HCTZ • Diuretic • Combination HCTZ and K+ sparing • Dry mouth

  21. #19, #13 - #20 Cephlexin #27 • Cephlosporin • Staph activity • Cross-reacts - allergy with penicillin – 5 -15%

  22. #20 Celebrex • Celecoxib • Selective Nsaid\Cox II inhibitor • Analgesia

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