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DIAGNOSTIC ERRORS OF PSEUDOTUBERCULOSIS Научный руководитель: к.ф.н., доцент Бойцова И.И Подготовил: 609 гр. леч . факультет Бочарников А.А. Владивосток 2012 г. БГОУ ВПО ВГМУ Минздравсоцразвития РФ Кафедра иностранных языков. Yersinia pseudotuberculosis (PT) (FESLF).
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DIAGNOSTIC ERRORS OF PSEUDOTUBERCULOSISНаучный руководитель: к.ф.н., доцент Бойцова И.ИПодготовил: 609 гр. леч. факультет Бочарников А.А. Владивосток 2012 г. БГОУ ВПО ВГМУ Минздравсоцразвития РФ Кафедра иностранных языков
Yersiniapseudotuberculosis (PT) (FESLF) It’s a Gram-negative bacterium that causes Pseudotuberculosis (Yersinia) disease in animals; humans occasionally get infected zoonotically, most often through the food-borne route
The currency of the research PT is a wildly spread disease both in the world and in Russia. PT is the disease which reveals itself mainly in the form of epidemic flashes of various intensity and it takes the third place among the infectious diseases. It occurs too often among the numerous feral-herd infections of the Far East. The variety of clinical forms masking PT under the other diseases of an infectious and noninfectious etiology complicate clinical diagnostics of PT.
The purpose of my report is to make the analysis of errors in the diagnostics of PT on the materials of infectious department of Regional Clinical Hospital №2 in Vladivostok and infectious hospital of Pacific Ocean Fleet for the period from 2005 to 2011.
The problems to be discussed are: • Estimation of clinical manifestations in case of PT • Finding out main symptoms of the disease • Analyzing errors in making of PT diagnostics
Research material was based on the supervision of 142 examined patients among which 111 patients were men (78%), 31 - women (22%) with PT diagnosis . The age of the patients under investigation was from 14 till 73 years. But PT diagnosis was confirmed only in 18 patients (13%) from 142 examined ones. It was confirmed by serological method of hemagglutination-inhibition reaction (title 1:200-1:1600). In 124 patients (87%) PT diagnosis wasn't proved.
The materials of the research The materials were based on the patient’s case histories and patients taken from infectious department of Regional Clinical Hospital №2 and infectious hospital of Pacific Ocean Fleet for the period from 2005 to 2011.
Summary • The variety of clinical forms masking PT under the other disease of an infectious and noninfectious etiology complicate clinical diagnostics of PT. • The clinical course of PT has mixed form of manifistation (44% patients) andmildcourse ( 66% patients). • The main syndromes of PT are: rash 59%, weakness 25%, sore throat 15%, arthralgia 13%, shivering 10%, diarrhea 10%. • The diseases masked under PT are: Allergic dermatitis 13,9%, UTRI 30,6% Intestinal yersinios 55,5%.
Recommendations The polymorphism of clinical manifestations, low quality of laboratory data in making the diagnosis of PT, makes it necessary to improve modern methods of diagnostics in this group of patients.
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