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(A) Patients with baseline NIHSS of 0 to 4

Figure e-1. Combined effects of intra/extracranial vascular occlusive lesion and leg weakness or extinction/inattention on unfavorable outcome. (A) Patients with baseline NIHSS of 0 to 4. p<0.001. p=0.001. Risk of an unfavorable outcome. p<0.001. - -. - +. + -. + +.

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(A) Patients with baseline NIHSS of 0 to 4

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  1. Figure e-1. Combined effects of intra/extracranial vascular occlusive lesion and leg weakness or extinction/inattention on unfavorable outcome (A) Patients with baseline NIHSS of 0 to 4 p<0.001 p=0.001 Risk of an unfavorable outcome p<0.001 - - - + + - + + Intra- or extracranial vascular lesion Leg weakness or extinction/inattention n=1031 n=436 n=345 n=129 (B) Patients with baseline NIHSS of 0 to 5 p<0.001 p<0.001 Risk of an unfavorable outcome p<0.001 - - - + + - + + Intra- or extracranial vascular lesion Leg weakness or extinction/inattention n=1105 n=582 n=373 n=173 The risk of an unfavorable outcome was calculated using ‘patients without both’ as the reference, adjusting for female sex, age ≥72 years, onset to admission time ≤12 hours, dyslipidemia, facial palsy, and sensory items of the National Institutes of Health Stroke Scale (NIHSS) in patients with baseline NIHSS score of 0 to 4 (A) and 0 to 5 (B) in the SUMO (Stroke Unit Multicenter Observational) Study cohort.

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