Clinicians, Collaboration & Big Data: Exploring the New MDT

1. Clinicians, Collaboration & Big Data: Exploring the New MDT Dr Catherine Kelly, Aridhia/UCLPartners Dr Rachel Knight, Aridhia

2. Clinician informatician Why are they needed? Role in the commercial biomedical informatics sector Challenges Future requirements

3. Informationto enable integrated care • Information systems to access key data on individuals and populations • Integration of care across organisational boundaries accessible by multidisciplinary teams • Monitoring of patient cohorts • Stratification of patients by risk • Active management of high-risk patients with complex needs • Empowering patients to self-manage • Evidence-based pathways and protocols Community Health System Resources & policies Organisation of Health Care Delivery systemdesign Decision support Clinicalinformation system Self-managementsupport Proactive, prepared practice team Informed, active patients Productive Interactions Functional and clinical outcomes

4. NHS: data rich but information poor “Most healthcare organisations at present have very little capacity to analyse, monitor, or learn from safety and quality information. This gap is costly, and should be closed.” Berwick Review “The NHS needs to invest more in developing analytic skills and informatics leadership. Clinicians are part of the solution both to system development and to better understanding data.” “Turning data into well understood, useful information is hard. But cleaning up the data rich, information poor pool holds out the promise of using information to inform practice, research and public health, to make it clear what quality means and where the NHS might be at risk of failing to deliver it.” Source: Round table report: the DRIP effect, EHI Insider, June 2013

5. Stratified medicine hits mainstream

6. We face a tidal wave of data Current Costs 2011 1.8 zettabytes 35% of all digital data is healthcare related 2020 90 zettabytes Future Approaches Needed for accessing, manipulating, visualising Requires entirely new perspective Emergent evidence for clinical validation, clinical utility & patient stratification Full genome sequence ~£3,000 [2012] Dropping in price 10x every 2-4 years Existing NHS genetic test ~£1,000 Disk cost to store raw sequence ~£100 Disk cost to store individuals variations ~10p

7. Data analysis and interpretation Source: Committee on A Framework for Developing a New Taxonomy of Disease; National Research Council

8. Multidisciplinary skillset required

9. Future collaborative approach required • Industry led collaborations • New forms of partnership working • Clinical informatics leadership • Commercialisation of innovation

10. Clinicians in commercial sector Challenges Adapting to work in different environment People communicate in different languages Persuading colleagues to listen Commercial vs healthcare drivers Benefits • Understand clinical environment and challenges • Domain expertise • Translate clinical requirements • Facilitate communications with different stakeholders • Business skills and commercial awareness

11. Conclusions

12. THANK YOU