1 / 11

Hair Cell and Meddis Hair Cell Model

Hair Cell and Meddis Hair Cell Model. Xiaoxiang Gong. Outline. Function of Hair Cells Hair Cell Model – Meddis Model Simulation Result for the Meddis Model Phase Locking. Function of Hair Cell. Meddis Model for Hair Cell. Synaptic cleft Outside the Hair cell. Hair cell.

corina
Download Presentation

Hair Cell and Meddis Hair Cell Model

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Hair Cell and Meddis Hair Cell Model Xiaoxiang Gong

  2. Outline • Function of Hair Cells • Hair Cell Model – Meddis Model • Simulation Result for the Meddis Model • Phase Locking

  3. Function of Hair Cell

  4. Meddis Model for Hair Cell Synaptic cleft Outside the Hair cell Hair cell • Spike Probability is proportional to the amount of transmitter in the synaptic cleft.

  5. Simulation Result for Meddis Model -- from Auditory Toolbox • Stimulus: Single tone (1KHz) with amplitude scales on silent background. • Spontaneous rate • Onset rate: the initial peak value • Steady state rate: adaptation level

  6. Phase Locking • The auditory nerve will tend to fire at a particular phase of a stimulating low-frequency tone (Period Histogram). So the inter-spike intervals tend to occur at integer multiples of the periods of the tone (Inter-spike Interval Histogram). • Phase locking depends on the stimulus frequency: with high frequency tones (> 3kHz) phase locking gets weaker.

  7. Phase Locking-- Construction of Period Histogram

  8. Phase Locking-- Period Histogram & Inter-spike Interval Histogram AN fibers fire at integer multiples of the stimulus period, not necessarily on every period

  9. Phase Locking-- Period Histograms from Meddis Model • Showing a half-wave rectified version of the stimulus

  10. Phase Locking-- Inter-spike Interval Histograms from Meddis Model • AN fibers fire at intervals related to stimulus frequency. For 1KHz sinusoid input

More Related