1 / 13

Tritrichomonas foetus in a cat

Tritrichomonas foetus in a cat. * Lisa Pohlman , *Marjory Artzer , **Verona Chaffin. * Kansas State University, Department of Diagnostic Medicine/Pathobiology, **Allcare Animal Hospital, Shawnee,KS. History; 16-week-old intact female, Bengal (Poppy). RDVM December 28, 2007

cortez
Download Presentation

Tritrichomonas foetus in a cat

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Tritrichomonas foetus in a cat *Lisa Pohlman, *Marjory Artzer, **Verona Chaffin *Kansas State University, Department of Diagnostic Medicine/Pathobiology, **Allcare Animal Hospital, Shawnee,KS Presented at SEVPAC 2008 – Permission granted for use on SEVPAC website only

  2. History; 16-week-old intact female, Bengal (Poppy) RDVM December 28, 2007 • Diarrhea, seromucoid nasal discharge & mild failure to thrive • De-wormed, antibiotics, SC fluids & sent home January 7th Recheck • Nasal discharge had cleared • Diarrhea worse → diagnosed coccidia • Albon January 11th Recheck • Diarrhea • Fecal wet mount → abundant motile organisms • A video recording of the organisms • A saline diluted, air-dried fecal smear Presented at SEVPAC 2008 – Permission granted for use on SEVPAC website only

  3. Presented at SEVPAC 2008 – Permission granted for use on SEVPAC website only

  4. Wright’s 100x • A variety of bacteria (mostly rods), debris, and protozoal organisms (9 to 12 um x 6 to 9 um) • with 3 anterior flagella, 1 posterior flagella,1 nucleus, undulating membrane, central axostyle Presented at SEVPAC 2008 – Permission granted for use on SEVPAC website only

  5. Further tests & Diagnosis • Culture (In PouchTM TF-Feline) • PCR • Tritrichomonasfoetus Presented at SEVPAC 2008 – Permission granted for use on SEVPAC website only

  6. Tritrichomonas foetus Trichomonads • Primitive eukaryotic organisms • Obligate protozoan symbionts • Multiple anterior flagella • Undulating membrane • Reproduction via binary fission • Trophozoites are transferred from host to host directly • Commensal & pathogenic species identified • Tritrichomonasfoetus -- pathogenic • Pentatrichomonashominis – non-pathogenic Presented at SEVPAC 2008 – Permission granted for use on SEVPAC website only http://vetsci.sdstate.edu/vetext/Trichomoniasis%20Range%20 Beef%20Cow%20Symposium%20web.htm

  7. Tritrichomonas foetus Cattle • Venereal pathogen Pigs • gastrointestinal tract & nasal mucosa • T. foetus = T. suis Dogs • Diarrhea Cats • Enteric pathogen of cats • Uterus Presented at SEVPAC 2008 – Permission granted for use on SEVPAC website only

  8. T. foetus; Enteric Pathogen in Cats • Colonizes colon • +/- observable symptoms • Chronic diarrhea • Feces dribble from anus • Young, densely housed cats • ~1/3 of the purebred feline population infected • Absence of diarrhea ≠ cat free of infection • Misidentified as • Giardia • Pentatrichomonas hominis Presented at SEVPAC 2008 – Permission granted for use on SEVPAC website only

  9. Pentatrichomonas Tritrichomonas Giardia spp. hominis foetus • Non-pathogenic • 5 anterior flagella http://vetsci.sdstate.edu/vetext/Trichomoniasis%20Range%20 Beef%20Cow%20Symposium%20web.htm Presented at SEVPAC 2008 – Permission granted for use on SEVPAC website only http://www.st.rim.or.jp/~samacha/ CareF/SickF/Protozo/Proto.html http://winnielovesus.blogspot.com/2007/09/ one-week-done-35-to-go.html

  10. Histologic Features of T. foetusM. J. Yaeger & J. L. Gookin, Vet Pathol 42:797-804 (2005) • Colonic trichomonads (6 sections recommended) • Lymphoplasmacytic & neutrophilic colitis • Eosinophils not a prominent feature • Crypt epithelial cell • Hypertrophy • Hyperplasia • ↑ mitotic activity • ↓ goblet cells • Crypt microabscesses • Attenuated superficial colonic mucosa • +/- Macrophages Presented at SEVPAC 2008 – Permission granted for use on SEVPAC website only

  11. Prognosis & Other Concerns Infected Cats • No effective antibiotic treatment • Overall health not adversely affected • ~90% diarrhea will stop within two years • Remain source of infection to other cats Hypothesis • Prolonged presence of organisms • Predisposition to IBD? Zoonotic Potential? • Human infection with T. foetus (1 case) • Immunosuppressed & previous stem cell transplantation Presented at SEVPAC 2008 – Permission granted for use on SEVPAC website only

  12. M. J. Yaeger and J. L. Gookin Vet Pathol 42:797-804 (2005) With Permission Unresponsive to antimicrobial treatment T.foetus PCR Histopathology Min. 6 sections Culture In PouchTM TF media • Saline diluted feces • Motile organisms • Air dried smear Presented at SEVPAC 2008 – Permission granted for use on SEVPAC website only

  13. Acknowledgements • Shon Koenig • Shelly Christenson • Nathan Rodriguez Presented at SEVPAC 2008 – Permission granted for use on SEVPAC website only

More Related