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Production of Test Aerosols. Reading: Chap 21. Q: In our daily life, do we generate aerosols? Q: What are the criteria for producing aerosols for testing?.
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Production of Test Aerosols Reading: Chap 21 Q: In our daily life, do we generate aerosols? Q: What are the criteria for producing aerosols for testing? • Ideal aerosol generator: a constant and reproducible output of (monodisperse), stable, uncharged, (solid), spherical aerosol particles whose size and concentration can be easily controlled. Aerosol & Particulate Research Laboratory
Atomization of Liquids Q: Do we generate mono- or poly-disperse droplets by atomization? Mass conc. of 5-50 g/m3 MMDs of 1-10 mm g of 1.5-2.2 Q: Can we produce high conc. aerosol by atomization? Q: What type of aerosols do we generate? • Liquid • Solution • Suspension Q: Do the solution’s properties change after a while? Aerosol & Particulate Research Laboratory
Ultrasonic Nebulizer Q: How does the particle size change wrt air velocity, viscosity and surface tension? Metered Dose Inhaler (MDI) Compressed Air Nebulizer Q: If dry particles are produced from nebulizing liquid, how does the g compare to that of the liquid? http://aerosol.ees.ufl.edu/Healthaerosol/section03-2.html Aerosol & Particulate Research Laboratory
Vibrating Orifice Aerosol Generator (VOAG) Q: How can we control droplet size? Aerosol & Particulate Research Laboratory
Spinning Disc Aerosol Generator http://www.bgiusa.com/img/stag2.jpg Q: How can we control droplet size? Aerosol & Particulate Research Laboratory
Electrospray http://www.newobjective.com/electrospray/ Aerosol & Particulate Research Laboratory
Atomization of Liquid Suspension Liquid suspension containing monodisperse solid particles of known size. Q: More than 1 particle present in a droplet? Aerosol & Particulate Research Laboratory
Considering the size distribution of droplets ….. (R: ratio of singlets to droplets containing particles) Aerosol & Particulate Research Laboratory
Wright Dust Feeder Dispersion of Powders • Requirement: • a means to continuously • metering a powder into the • generator at a constant rate • a means to dispersing the powder • Common methods: • High velocity air stream • Scraper • Fluidized bed generator Aerosol & Particulate Research Laboratory
Fluidized Bed Aerosol Generator • Dispersibility depends on: • Powder material • Particle size • Shape • Moisture content Dry Powder Inhaler (DPI) http://aerosol.ees.ufl.edu/Healthaerosol/section04-2.html Aerosol & Particulate Research Laboratory
Condensation Methods Basic principle to generate monodisperse aerosol: allow condensation to occur under slow and controlled condition Q: How do we control the particle size? Aerosol & Particulate Research Laboratory
Reflections Aerosol & Particulate Research Laboratory