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Next Generation Sequencing

Creative Biogene brings pharmaceutical and biotech companies next generation sequencing service. Learn more from https://www.creative-biogene.com/services/next-generation-sequencing.html

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Next Generation Sequencing

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  1. TheApplicationofNextGenerationSequencing Comparedwiththetraditionalsequencingtechnology,thenextgenerationsequencing(NGS) technologyhasstrongadvantagesofultra-highspeed,highthroughput,lowcostandhigh efficiency.Thedevelopmentofthisemergingtechnologyandtheestablishmentofanew generationofsequencingplatformhavehadasignificantimpactongenomeresearch,human healthandsocialcognition.Thebookconsistsoffivepartsand18chapters.Thefirstpartandthe secondpartrespectivelysummarizetheworkingprinciple,methodandcharacteristicsofthe traditionalsangerDNAsequencingandthenewgenerationsequencingplatform.Thethirdpart analyzesthebottleneckofsequencingtechnologyanditssolution.Thefourthpartintroducesthe commercialapplicationofsequencingandtheemergingsequencingplatform.Thefifthpart discussesthewideapplicationofthenewgenerationsequencingtechnologyingenomics research."Next-generationgenomesequencing:towardpersonalizedmedicine,"writtenby researchersandinventorsinvolvedinthedevelopmentandapplicationofNGStechnology,isthe world'sfirstbooktointroducethenewgenerationofDNAsequencingtechnology.Itcanbeused asareferencebookforteachers,studentsandresearchersinthefieldsofbiology,medicineand agronomyincollegesanduniversities.Itcanalsoenlightenandhelpreaderswhowantto understandpersonalgenomeinformation,personalizedmedicine,ethicsandotherissues. DNAsequencingtechnologyresearch,developmentandprogress,inalltheresearchfieldoflife scienceshowsitsspecialcharm.Inthispaper,combingthedevelopmentofDNAsequencing technologypulseroad,thefirstgenerationofsequencingtechnologywasintroducedindetailthe sangeralibrary,chemicaldegradationandRoche454sequencingmethodofthesecond

  2. generationsequencingtechnology,IlluminaSolexasequencingmethod,theABISOLIDsequencinggenerationsequencingtechnology,IlluminaSolexasequencingmethod,theABISOLIDsequencing method,andthethirdgenerationsequencingtechnologyofsinglemoleculefluorescence sequencingmethod,thenanoporesequencingmethod,andanalyzesNextGeneration Sequencingandthecharacteristicsofsequencingtechnology,pointsoutthatthegenerationof DNAsequencingtechnologyandtherapiddevelopmentoflifescienceresearchhasbroughtthe revolutionarychange,makethehumantonatureandtheirowncognitiveenteredtoanew scientificlevel. Newgenerationsequencingtechnologies(NGS)cangeneratehigh-throughputrna-seqdataand furtherstudythetranscriptome,including454,illumina,SOLiDandIonTorrenttechnologies,and advancedsingle-moleculelong-readssequencingmethods,includingPacBioandnano-pore sequencing(nanoporesequencing).Theeaseofuseofhigh-throughputsequencinghaslong noncoding(IncRNA)toidentifypossible,accordingtolocatetheseIncRNAgenomecanbedivided intogene,gene,betweensenseandantisenseandtwo-wayIncRNA,IncRNAtranscriptioninthe plantthroughthepolymeraseII,IVandV,orientationofDNAmethylationandRNA(RdDM) targetingepigeneticregulation(regulategeneexpressionthroughhistonemodification, chromosomeannularizationandothermechanisms).TheadvantagesofNGSisfast,repeatable andhigh-precisionsequencingtechnology.

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