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Anti Bevacizumab monoclonal antibody can be provided from Creative Diagnostics.t<br><br>https://www.creative-diagnostics.com/Anti-Bevacizu-antibody-249157-160.htm<br>
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Anti-Bevacizumab monoclonal antibody (CABT- Anti-Bevacizumab monoclonal antibody (CABT- BL427) BL427) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION PRODUCT INFORMATION Immunogen Immunogen Avastin Isotype Isotype Fab monovalent Source/Host Source/Host Human Species Reactivity Species Reactivity N/A Conjugate Conjugate Unconjugated Applications Applications ELISA Format Format Liquid Buffer Buffer Phosphate buffered saline Preservative Preservative None Storage Storage Store at +4°C. DO NOT FREEZE. This product should be stored undiluted. Should this product contain a precipitate we recommend micr°Centrifugation before use. BACKGROUND BACKGROUND Introduction Introduction Bevacizumab (trade name Avastin, Genentech/Roche) is an angiogenesis inhibitor, a drug that slows the growth of new blood vessels. Bevacizumab is a recombinant humanized monoclonal antibody that blocks angiogenesis by inhibiting vascular endothelial growth factor A (VEGF-A). VEGF-A is a chemical signal that stimulates angiogenesis in a variety of diseases, especially in cancer. Bevacizumab was the first clinically available angiogenesis inhibitor in the United States. Bevacizumab was approved by the U.S. Food and Drug Administration (FDA) for certain metastatic cancers. It received its first approval in 2004, for combination use with standard chemotherapy for metastatic colon cancer. It has since been approved for use in certain lung cancers, renal cancers, ovarian cancers, and glioblastoma multiforme of the brain. It had been approved for breast cancer, but that approval was withdrawn when later studies showed no 45-1 Ramsey Road, Shirley, NY 11967, USA Email: info@creative-diagnostics.com Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved
evidence of effectiveness. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. It is listed for its use in treating certain eye diseases. 45-1 Ramsey Road, Shirley, NY 11967, USA Email: info@creative-diagnostics.com Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved