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c3a receptor antibody

Mouse anti Human C3a Receptor antibody, clone hC3aRZ1 recognizes the receptor for human complement component C3a (C3aR), a 55kD cell surface protein of the rhodopsin family of G protein-coupled seven-transmembrane receptors.<br>https://www.creative-diagnostics.com/Anti-C3a-RECEPTOR-Mab-RPE-conjugated-234628-491.htm<br>

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c3a receptor antibody

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  1. Anti-C3A Receptor monoclonal antibody, clone Anti-C3A Receptor monoclonal antibody, clone hC3aRZ1 [R-PE] (CABT-45020MH) hC3aRZ1 [R-PE] (CABT-45020MH) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION PRODUCT INFORMATION Product Overview Product Overview Mouse anti Human C3a Receptor antibody, clone hC3aRZ1 recognizes the receptor for human complement component C3a (C3aR), a 55kD cell surface protein of the rhodopsin family of G protein-coupled seven-transmembrane receptors. C3a is an anaphylatoxin, which is a potent proinflammatory mediator that possesses immunoregulatory properties. C3a regulates inflammatory functions by binding to the C3a receptor. C3aR is expressed on various tissues and leucocytes including basophils, neutrophils, mast cells, eosinophils and activated T lymphocytes. Expression levels of C3aR on human cells varies significantly between donors. Flow Cytometry Use 10ul of the sugested working dilution to label 1x106 cells in 100ul. Specificity Specificity C3a RECEPTOR Immunogen Immunogen Recombinant human C3aR protein Isotype Isotype IgG1 Source/Host Source/Host Mouse Species Reactivity Species Reactivity Human Clone Clone hC3aRZ1 Conjugate Conjugate R-PE Applications Applications FC Procedure Procedure Conjugated Antibodies Format Format Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised Size Size 100 Tests Preservative Preservative 0.09% Sodium Azide 1% Bovine Serum Albumin 5% Sucrose Storage Storage Store at +4°C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. Warnings Warnings For research purposes only 45-1 Ramsey Road, Shirley, NY 11967, USA Email: info@creative-diagnostics.com Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved

  2. GENE INFORMATION GENE INFORMATION Gene Name Gene Name C3AR1 complement component 3a receptor 1 [ Homo sapiens (human) ] Official Symbol Official Symbol C3AR1 Synonyms Synonyms C3AR1; complement component 3a receptor 1; AZ3B; C3AR; HNFAG09; C3a anaphylatoxin chemotactic receptor; C3a-R; complement component 3 receptor 1; C3A RECEPTOR; Entrez Gene ID Entrez Gene ID 719 mRNA Refseq mRNA Refseq NM_004054 Protein Refseq Protein Refseq NP_004045 MIM MIM 605246 UniProt ID UniProt ID Q16581 Chromosome Location Chromosome Location 12p13.31 Pathway Pathway Class A/1 (Rhodopsin-like receptors); Complement and Coagulation Cascades; Complement and coagulation cascades; Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD); Disease; G alpha (i) signalling events; GPCR downstream signaling; GPCR ligand binding; Function Function C3a anaphylatoxin receptor activity; G-protein coupled receptor activity; complement component C3a receptor activity; phosphatidylinositol phospholipase C activity; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: info@creative-diagnostics.com Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved

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