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c4b antibody

Anti-C4B monoclonal antibody can be provided from Creative Diagnostics.<br>https://www.creative-diagnostics.com/Anti-C4B_2-MAb-186106-144.htm<br>

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c4b antibody

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  1. Anti-C4B monoclonal antibody, clone UEN48 Anti-C4B monoclonal antibody, clone UEN48 (DCABY-643) (DCABY-643) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION PRODUCT INFORMATION Antigen Description Antigen Description This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. This GeneID and its associated RefSeq record represent a second copy of C4B found on ALT_REF_LOCI_7. Specificity Specificity Mouse anti Human C4d antibody, clone UEN48 recognizes human complement factor C4d, a degradation product of the activated complement factor C4b. Isotype Isotype IgG1 Source/Host Source/Host Mouse Species Reactivity Species Reactivity Human Clone Clone UEN48 Conjugate Conjugate Unconjugated Applications Applications ELISA, Immunohistology-Paraffin Preparation Preparation Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant Format Format Purified IgG - liquid Size Size 100 μg Buffer Buffer Phosphate buffered saline Storage Storage Store at +4°C or at -20°C if preferred.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature 45-1 Ramsey Road, Shirley, NY 11967, USA Email: info@creative-diagnostics.com Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved

  2. the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. GENE INFORMATION GENE INFORMATION Gene Name Gene Name C4B_2 complement component 4B (Chido blood group), copy 2 [ Homo sapiens (human) ] Official Symbol Official Symbol C4B_2 Synonyms Synonyms C4B_2; complement component 4B (Chido blood group), copy 2; complement C4-B-like Entrez Gene ID Entrez Gene ID 100293534 mRNA Refseq mRNA Refseq NM_001242823 Protein Refseq Protein Refseq NP_001229752 UniProt ID UniProt ID P0C0L5 Chromosome Location Chromosome Location chromosome: 6 45-1 Ramsey Road, Shirley, NY 11967, USA Email: info@creative-diagnostics.com Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved

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