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pasteurella multocida toxin

Active Pasteurella multocida toxin full length protein.t<br>https://www.creative-diagnostics.com/Active-Pasteurella-multocida-toxin-protein-175853-434.htm<br>

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pasteurella multocida toxin

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  1. Pasteurella multocida Active Pasteurella multocida Pasteurella multocida Active Pasteurella multocida toxin (full length) (DAG-P2722) toxin (full length) (DAG-P2722) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION PRODUCT INFORMATION Product Overview Product Overview Active Pasteurella multocida toxin full length protein Antigen Description Antigen Description Pasteurella multocida toxin (PMT) is produced by a gram-negative bacillus, Pasteurella multocida. PMT activates the Gq and G12/13 dependent signaling pathways. Gq and G12/13 are alpha subunits of the GTP trimer bound protein of animal cells. It does not activate the G11 dependent pathway although G11 is similar to Gq. This toxin binds to an unidentified receptor and then is introduced into the cells by endocytosis and starts to function then. Therefore it does not function on cells without the receptor or defective in the endocytosis pathway. Nature Nature Recombinant Expression System Expression System E. coli Species Species Pasteurella multocida Purity Purity > 90 % by SDS-PAGE. Conjugate Conjugate Unconjugated Applications Applications SDS-PAGE Cellular activity WB ELISA Cellular Localization Cellular Localization Cytoplasmic Bio-activity Bio-activity Induction of aggregation of Swiss 3T3 cells by incubation with PMT. Format Format Liquid Buffer Buffer Preservative: None Constituents: 50% Glycerol, 0.1M Sodium chloride, 5mM Tris HCl, pH 7.5 Storage Storage Store at -20°C. Stable for 12 months at -20°C Preservative: None Constituents: 50% Glycerol, 0.1M Sodium chloride, 5mM Tris HCl, pH 7.5 This product is an active protein and may elicit a biological response in vivo, handle with caution. BACKGROUND BACKGROUND Introduction Introduction Pasteurella is a genus of Gram-negative, facultatively anaerobic bacteria. Pasteurella species 45-1 Ramsey Road, Shirley, NY 11967, USA Email: info@creative-diagnostics.com Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved

  2. are non-motile and pleomorphic. Most species are catalase-positive and oxidase-positive. Keywords Keywords Dermonecrotic toxin; DNT; Mitogenic toxin; PMT; ToxA; P. multocida toxin; Pasteurella multocida toxin 45-1 Ramsey Road, Shirley, NY 11967, USA Email: info@creative-diagnostics.com Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved

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