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The Immune System: Protector of the human body. The immune system functions as the body’s defense against invaders. Virus: herpes virus. Bacteria: streptococci. Protozoa: Plasmodium. Parasite: schistosome. SARS virus. Fungus Candida. Organs of the Immune System . Tonsils and adenoids.
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The Immune System: Protector of the human body
The immune system functions as the body’s defense against invaders Virus: herpes virus. Bacteria: streptococci. Protozoa: Plasmodium Parasite: schistosome. SARS virus Fungus Candida
Organs of the Immune System Tonsils and adenoids Lymph nodes Lymphatic vessels Thymus Lymph nodes Spleen Peyer’s patches Appendix Lymph nodes Bone marrow Lymphatic vessels
Lymphatic System Lymph node Lymphatic vessel
Epithelial cell Muscle cell Epitope Antigen Bacteria Antibody SARS virus Self vs.Nonself Non-self nerve cell Leukocyte Nerve cell Epitope Class I MHC protein Antigen Class I MHC self-marker protein Antibody
First line of defence The barricade Human Body tears antibacterial enzymes saliva antibacterial enzymes mucus linings traps dirt and microbes skin prevents entry stomach acid low pH kills harmful microbes “good” gut bacteria out compete bad
Second line of defence Non-specific patrol phagocytes Monocyte: circulate in the blood Eosinophil neutrophils Mast cell not a blood cell allergy symptoms Macrophage: secrete signals important in immune response Dendritic cell: stationary monitors Neutrophil: blood cell can move into tissues as needed Basophil
What’s in a pimple? Accumulation of dead phagocytes, destroyed bacteria and dead cells eeeoooooo!!!!
Second line of defence Natural Killer cells Killer cell Target cell Target-oriented granules Surface contact
The Immune Response Part of the second line of defense Inflammation Fever
Third line of defence “Wanted dead or alive” Antigen-specific B cell receptor Class II MHC and processed antigen are displayed Antigen Antibodies B cell Lymphokines Plasma cell Antigen-presenting bacteria Activated helper T cell B lymphocytes
Third line of defence “Wanted dead or alive” Resting helper T cell Resting cytotoxic T cell T lymphocytes Activated helper T cell Activated killer T cell
Antibodies & Immunoglobulin “BOOK ‘EM DANO!” IgG, IgD, IgE, and IgA IgA IgM
The Immune System is key in helping the body maintain Homeostasis
Pediatric office Posters • Create a poster depicting an assigned part • of the immune system. • Your poster should educate youngsters • about their immune system. • Bonus points available for description of a disease or disorder associated with that part of the immune system Composition Books Create a table that includes the structures and function of the three lines of defense.