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Chapter 8 . Cell Growth. In most cases, a living thing grows because it produces more and more cells. Limits of Cell Growth. Number 1. Cell membrane- food oxygen and water enter and wastes leave. How fast things enter and leave depends on the surface area
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Chapter 8 Cell Growth
In most cases, a living thing grows because it produces more and more cells
Number 1 Cell membrane- food oxygen and water enter and wastes leave
How fast things enter and leave depends on the surface area How fast products are used up and waste is produced depends on the volume
Fig 8-2 • Surface Area and volume do not increase at the same rate so this is a problem
Number 2 • DNA’s ability to direct the function of the cell becomes limited
The Solution: Cell Division • The process where by the cell divides into two daughter cells • Draw picture in notes
Controls on Cell Growth • Cell behavior – cell growth and cell division are carefully controlled • Heart and nervous system – cells rarely divide
When cells come in contact with other cells they tend to stop growing
Cell growth can be turned on • Example – a cut, broken bone • Cell growth stops when fixed
Uncontrolled Cell Growth • Results are severe • Cancer – disorder where cells have lost the ability to control their own growth
Eukaryotic Cells • Nucleus and membrane bound organelles • Eukaryotic cells divide in two steps
1. Mitosis – the process by which the nucleus of a cell is divided into 2 nuclei, each with the same number and kinds of chromosomes as the parent cell
2. Cytokinesis – process of the cytoplasm dividing to form 2 new cells
The process is complex • Large amounts of DNA need to be separated. • Each cell needs one copy of a chromosome
Chromosomes • Structures in the cell that contain the genetic information that is passed from one generation to the next
The cells of different organisms contain different numbers of chromosomes • Humans – 46 • Goldfish – 94 • Dog – 78 • Cat – 32
Chromosome Structure • Ready to divide • DNA replicated • Chromosomes become visible by condensing
The chromosome has two identical parts – 2 Chromatids The chromosome has two identical parts – 2 Chromatids
The two chromatids are often called sister chromatids • Centromere – holds sister chromatids together
The period of time from one mitosis to the next • A cell grows, prepares for division, and divides to form two daughter cells • Includes mitosis
` Mitosis – M phase
Interphase • G1 – growth and activity • S- DNA replication • G2 – growth and activity
Some cells in the body go through the cell cycle every 6 hours • Some cells never do (nerve and muscle)
Interphase • Long • Period between cell divisions • 3 phases – G1, S, G2 • G1 – (gap1) – growth and development
S (DNA synthesis phase) – replication • Proteins associated with chromosomes are also made • G2- gap 2 – shortest phase • Synthesis of materials needed for cell division
During interphase the cell is active • Proteins are made • DNA is copied • ATP is made and used • Cells that are specialized do their thing • Example - secretion
Prophase (Ready) • Metaphase (Middle) • Anaphase (away) • Telophase (two)
Prophase • Longest phase • 50-60% of total mitosis time • Chromosomes become visible – coil tightly • Centrioles separate and move to opposite sides
Chromosomes attach to the spindle • Nucleolus disappears • Nuclear envelope breaks down
Spindle • Meshlike structure that develops from the centrioles • Helps chromosomes move
Metaphase • Shortest – few minutes • Chromosomes line up at the center of the cell
Anaphase • Centromeres that join sister chromatids split • Sister chromatids separates into individual chromosomes • Chromosomes separate into two groups near the poles
Telophase • Chromosomes loosen up – go back to chromatin • Occurs in the area where the nucleus will form • Nuclear envelope reforms • Nucleolus becomes visible • Mitosis is over