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Hepatitis E the emerging infectious disease in developing countries. Lida Bun 10/31/2012 Brother Thomas McPhillips Microbiology in the News. Hepatitis E characteristics and how does it spread?. Virus family: Caliciviridae Nucleic Acid: RNA (+ sense) Disease caused: Enteric non-A,
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Hepatitis Ethe emerging infectious disease in developing countries Lida Bun 10/31/2012 Brother Thomas McPhillips Microbiology in the News
Hepatitis E characteristics and how does it spread? • Virus family: Caliciviridae • Nucleic Acid: RNA (+ sense) • Disease caused: Enteric non-A, • non-B hepatitis • Size: 30-35 nm, icosahedral • Envelope: Non-envelope • Incubation period: 3-8 weeks • Transmission: The hepatitis E virus is transmitted mainly through the faecal-oral route due to faecal contamination of drinking water. • Ingestion of contaminated meat • Transmission to pregnant woman to her fetus • Transfusion of infected blood
Where and who does it effect mostly? • 20 million cases of infection per year. • 3 million acute illnesses and 70,000 deaths annually • Common in people 15 to 40 yrs old. • Hepatitis E is prevalent in most developing countries. • Particularly chronic in pregnant women. • Symptoms
Can HEV be treated? • No treatment as of right now • “Self-limiting” disease • Support • Prevention
What is Hecolin? • Recombinant Hepatitis E Vaccine (Escherichia Coli) Developed by Xiamen University and Xiamen Innovax Biotech Co. Ltd • First China’s State Food and Drug Administration (CSFDA) approved vaccine affective for HEV under mass production. • Inoculation of this product can stimulate the body to produce immunity against hepatitis E virus for the prevention of hepatitis E. • This product is suitable for susceptible population aged 16 and above.