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The Inheritance of Mutant Traits

The Inheritance of Mutant Traits. Drosophila Culturing. Objective. Determine the pattern of inheritance of mutant traits in Drosophila melanogaster (fruit flies). The pattern of inheritance will either show... incomplete dominance or reveal the dominant and recesssive strains

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The Inheritance of Mutant Traits

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  1. The Inheritance of Mutant Traits Drosophila Culturing

  2. Objective Determine the pattern of inheritance of mutant traits in Drosophila melanogaster (fruit flies) • The pattern of inheritance will either show... • incomplete dominance or reveal the dominant • and recesssive strains • sex linkage or autosomal inheritence

  3. Why Fruit Flies? Takes up little space Produce numerous offspring Many genes to study & experiment Easy to Culture Low rate of mutations New generation every 2 - 3 weeks

  4. adult male adult female Drosophila Life Cycle Egg Larva Pupa Adult

  5. Sex Determination in Drosophila: Comparing Abdomens Female Male Males smaller, rounder abdomen dark posterior generally smaller sex combs Females large pointed abdomen light posterior generally larger no sex combs Male Sex Combs Sex combs on front legs

  6. Mutant: Normal: Apterous (mutant) Winged (wild) trait ap = apterous or wingless (mutant type) + = normal wings (wild type) alleles

  7. P1 Cross: Wild males (normal wings) Apterous (females) (wingless) phenotypes X + + ap ap X genotypes + = normal wings (wild type) Ap = apterous or wingless (mutant type)

  8. F1 Cross: What is the dominant trait? What is the recessive trait? What % of traits will be expressed in the F2?

  9. More Mutant Traits: White eyes Vestigial

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