Cernos 1% W/W Gel

1. Introduction to Cernos 1% Gel Cernos Gel is a medicine used in the treatment of male hypogonadism caused due to low testosterone levels. It is only prescribed to men with known medical conditions. It helps in restoring the level of testosterone in the male body. Cernos Gel is for external use only. It should be applied on arms and shoulder once a day, preferably at the same time every day. It should be used as your doctor’s advice. You should use this medicine for as long as it is prescribed for you. Do not use the gel too often and avoid applying it over the genital area. The most common side effects of this medicine include acne and application site reactions (burning, irritation, itching, and redness). If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Some side effects may mean you should stop taking this medicine shortness of breath, frequent or persistent erections, and low sperm count. Before taking this medicine, tell your doctor if you have ever had high blood pressure, heart attack, or stroke. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Your doctor might perform regular blood tests to keep track of testosterone, and prostate-specific antigen (PSA) levels. Uses of Cernos 1% Replacement therapy in males for conditions associated with deficiency/absence of endogenous testosterone, such as acquired or congenital primary hypogonadism and hypogonadotropic hypogonadism. How does Cernos 1% Gel Works? Cernos Gel works by replacing testosterone in adult male patients with hypogonadism (various health problems caused by a lack of testosterone, a natural male hormone). Thus, helps to improve clinical symptoms such as impotence, infertility, low sex drive, tiredness, depressive moods, bone loss caused by low hormone levels. Side Effects of Cernos 1% Common Side Effects

2. ● Burning or prickling sensation, dryness, rash, redness or itchiness at the site of application Swelling of hands or feet Headache High blood pressure Prostate changes Increased body hair growth Increase in breast size ● ● ● ● ● ● Rare Side Effects ● Signs and symptoms of the enlarged prostate gland or prostate cancer include increased urination at night, trouble starting your urine stream, having to pass urine many times during the day or urge to go to the bathroom right away and being unable to pass urine or weak urine flow Signs and symptoms of a blood clot in your legs or lungs can include leg pain, swelling or redness, difficulty breathing or chest pain Swelling of your ankles, feet or body, with or without heart failure Enlarged or painful breasts Signs and symptoms of heart attack or stroke Trouble breathing while you sleep (sleep apnoea) ● ● ● ● ● Dosage of Cernos 1% Gel Missed Dose Apply the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed dose. Overdose An overdose of this medicine is not likely to cause severe symptoms unless it is applied for a prolonged period of time in large volumes. However, the ingestion of this medicine may cause harm and immediate medical intervention may be required. How To Manage Side Effects Headache: Rest and relax. Drink plenty of fluids such as water or ORS (Oral Rehydrating Solution) and apply a pain-relieving balm on the head if necessary. Contact your doctor if the headache did not improve. Itchy skin:

3. Avoid hot baths because hot water can irritate your skin further. Do not scratch the affected area. Use sunscreen and wear protective clothing while going outside. Use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if the itching worsens. Warning & Precautions Pregnancy This medicine is not recommended for use in pregnant women. Breast-feeding This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Discuss all the risks and benefits with your doctor before using this medicine. General warnings Prostate cancer This medicine should be used with caution in geriatric patients due to an increased risk of prostate cancer. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition. Heart diseases This medicine should be used with extreme caution in patients with a known history of heart diseases due to the increased risk of a heart attack and stroke. Close monitoring of heart function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition. Polycythemia This medicine should be used with caution in patients with a known history of polycythemia (increased red blood cell count) due to the increased risk of worsening of the patient’s condition. Close monitoring of hemoglobin and hematocrit levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition. Hypercalcemia This medicine should be used with extreme caution in patients with a history of hypercalcemia (increased blood calcium levels), hyperparathyroidism (overproduction of parathyroid hormone in the body), or kidney dysfunction due to the increased risk of worsening of the patient’s condition. Close monitoring of calcium levels is recommended for such patients. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition. Testosterone abuse This medicine is not recommended for use in higher doses than prescribed. If testosterone abuse is suspected, frequent monitoring of serum testosterone levels should be done to ensure that they are in the therapeutic range.

4. Safety Advice Pregnancy UNSAFE Cernos Gel is highly unsafe to use during pregnancy. Seek your doctor’s advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby. Breast feeding UNSAFE Cernos Gel is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. Cernos Gel is not indicated for use in women. FAQs 1. What is the use of Cernos gel? Ans. For men, Low testosterone levels can result in Hypogonadism. It is treated with Sun Pharma’s Cernos Gel. It is prescribed by doctors only. 2. What does Testosterone gel such as Cernos do? Ans. It aids in raising the low level of Testosterone in men’s bodies. 3. Can females use Cernos gel? Ans. The body of a woman contains trace levels of the hormone testosterone. Testosterone gel, such as Cernos, can be prescribed in the circumstances like breast cancer and IVF treatment. Make sure you never use this gel without a doctor’s approval as a woman. 4. What are the other strengths and dosages of Cernos? Ans. It is offered as capsules made of gelatin and gel. The names of various doses are: ● ● ● Cernos Gel 1% Cernos Depot Injection Cernos 40 mg soft gelatine capsule

5. Testosterone strength in the gel version is 10 mg, but it is 40 mg in the pills.