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Evolution of multigene families. Gene duplication and multigene families. Orthologs - homologs by speciation. Paralogs - homologs by gene duplication. Phylogenetic consequences of duplication, speciation, and gene conversion in gene families.
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Gene duplication and multigene families Orthologs - homologs by speciation • Paralogs - homologs by gene duplication
Phylogenetic consequences of duplication, speciation, and gene conversion in gene families
Gene duplication and polyploidization in plants Poplar Papaya Arabidopsis
Retroposon-mediated duplication of IQD12 gene and morphological evolution in tomatoes
Using age distribution of gene duplication events to infer whole-genome duplications
Evidence for adaptive evolution in ribonuclease genes of primates
Evidence for localized gene conversion & concerted evolution in primate globin gene family
The vertebrate major histocompatibility complex (Mhc) Class I Class III Class II LMP TAP complement DQ DR DP DM DO DN HSP70 B C X E J A H G F Human B A A B A A B B B A B A B B B A I II III I TAP D Q T M complement K O F E M A LMP HSP70 Mouse B A B B B B A B B A II II I II I II B-G TAP B-G rDNA Chicken A B B B B B I II HSP70 complement LMP Frog I A B B B
Concerted evolution of avian Mhc genes revealed by Genetree analysis A, species tree B, gene tree
Phylogeny of bird and mammal Mhc class II B genes (exon3) 88 Agph-DAB1 Red-winged Blackbird Agph-DAB2 Agph1.1 96 Agph1.2 Agph1.3 Came.11 88 House Finch Came1.2 Came2.1 100 Apco1.1 Apco1.2 Apco1.3 Apco2.1 Apco3.6 birds Apco3.4 Scrub Jay Apco3.3 mammals 95 100 Apco3.2 Apco2.3 Apco2.4 Apco3.5 Apco3.1 Apco2.2 BLBI BLBII 100 100 CHKBLBETA chicken BLBIII BLBIV BLBVX HLA-DRB1 HLA-DRB7 HLA-DRB2 96 Mus-Eb mammals HLA-DOB Maru-DAB1 81 HLA-DPB Mus-Ab HLA-DQB Xenopus Xela-DAB Pore-DXB Poecilia 0.10 substitutions/site
The DDC model of subfunctionalization, as illustrated by Hox genes
Complementary expression patterns in duplicated zebrafish engrailed genes
} Using gene order to estimate times of gene duplication in yeast }
Paralogs clustering by species - a telltale sign of concerted evolution