Activation of T Cells: Helper and Cytotoxic

Feb 15, 2012

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Activation of T Cells: Helper and Cytotoxic

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22. Activation of T Cells: Helper and Cytotoxic

Antibiotics in Endodontics

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Chapter 10 Immune system

Chapter 10 Immune system. 1. Components. 1) Cells. ① Lymphocyte : a. T-lymphocytes : cytotoxic T cell: Tc C- kill the tumor cell, virus infective cell and foreign cell helper T cell: Th C- promotes activity of BLC and Tc C

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Harut Avakian

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Specific Immunity—3 rd line of defense

Specific Immunity—3 rd line of defense. Who are the players? Antigens Antibodies and B-cells Antibody editing and clonal selection Cytotoxic T-cells Helper T-cells MHC and antigen processing. Who are the players?. Antigens: foreign proteins, usually part of virus or bacteria

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Immune Response

Immune Response. Humoral Immune Response Activation of B-Cells to produce antibodies Cell-mediated Immune Response Activation of cytotoxic T-Cells. Active vs Passive Immunity. Active immunity… via natural exposure Relies on active production of antibodies through a pathway of steps

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Lecture outline

Lecture outline . Capture of antigens from sites of entry and display of antigens to T cells Function of MHC molecules as the peptide display molecules of adaptive immunity Recognition of protein antigens by different classes of T cells (helper vs cytotoxic) . Functions of T lymphocytes.

417 views • 31 slides

B-cells and T-helper cells

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Community Helpers

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T Lymphocytes (Type of White Blood Cell )

T Lymphocytes (Type of White Blood Cell ). Are called T cells because they are finalized in an organ called the thymus (part of immune system) but originally form in the bone marrow 4 types (Helper, Cytotoxic, Memory, Regulatory,) T cells differentiate in the bone marrow

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CELLS& ORGANS OF IMMUNE MECHANISM.

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Cytotoxic T Lymphocytes

Cytotoxic T Lymphocytes. CTLs can kill virus-infected cells. Here, a CTL (arrow) is attacking and killing a much larger influenza virus-infected target cell. http://www.cellsalive.com/. Models of CTL Response. dT/dt = l – dT – kVT dT*/dt = kVT – d V T* - d E ET* dV/dt = pT* - cV

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T helper cells in IBD

T helper cells in IBD. Jaimee Doucette. Overview. Background Information on T Helper cells What is known about Th cells in IBD? What is still unknown about Th cells in IBD? Paper 1 Paper 2 Future studies/specific aims. T cells. Nature Reviews Immunology 2 , 309-322 (May 2002).

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Lecture 11-Activation of naïve T cells. Naïve T cells are activated in lymph nodes and spleen. Dendritic cells are key antigen presenting cells for naïve T cells. Naïve T cells require MHC/peptide plus antigen-presenting cell "costimulation" in the form of B7 molecules.

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The Helper

The Helper. A Study of the Holy Spirit by Catherine Marshall. Part 2.5 How do I receive the Helper? Being willing to be put to work Page 69. How do I receive the Helper ? Being willing to be put to work. Mark 10:43-45

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Lymphocyte Activation Recognition David Straus dbstraus@vcu

Lymphocyte Activation Recognition David Straus dbstraus@vcu.edu Reading: Chpt 8-2, 8-3, 8-4, 8-11, 10-6. T cell activation: proliferation & differentiation. Activation of naïve T cells leads to their proliferation and differentiation into effector cells.

512 views • 28 slides

Enzymes: “ Helper ” Protein molecules

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The complete guide to antibody drug conjugates linkers

As one of the crucial components for ADC, antibody drug conjugate linker provides a specific bridge for the stable and efficient delivery of the cytotoxic drug to the target cells during the preparation and storage stages of the ADCs. An ideal linker is supposed to provide competent stability in the process of systemic circulation but take into the efficient and rapid release of the cytotoxic drug in an active form inside the tumor cells.

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Perforin Granzyme Apoptosis Pathway

Perforin/granzyme apoptosis pathway is the primary signaling pathway used by cytotoxic lymphocytes to eliminate virus-infected and/or transformed cells. Studies in gene-disrupted mice indicate that perforin, in combination with granzyme, could induce apoptosis. It is vital for cytotoxic effector function and has an indispensable, but an undefined role in granzyme-mediated apoptosis.

191 views • 1 slides

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Activation of T Cells: Helper and Cytotoxic

Activation of T Cells: Helper and Cytotoxic

Presentation Transcript

Antibiotics in Endodontics

Chapter 10 Immune system

Harut Avakian

Specific Immunity—3 rd line of defense

Immune Response

Lecture outline

B-cells and T-helper cells

Community Helpers

T Lymphocytes (Type of White Blood Cell )

CELLS&amp; ORGANS OF IMMUNE MECHANISM.

Cytotoxic T Lymphocytes

T helper cells in IBD

Immunology 2 nd Med 2009

组织胚胎学课件 七年制英文医学班专用

Inhibition of TGF-ß release from SHED Cells in Fibrodysplasia Ossificans Progressiva

Lecture 11-Activation of naïve T cells

The Helper

Biology and function of T cells

Lymphocyte Activation Recognition David Straus dbstraus@vcu

Enzymes: “ Helper ” Protein molecules

The complete guide to antibody drug conjugates linkers

Perforin Granzyme Apoptosis Pathway

CELLS& ORGANS OF IMMUNE MECHANISM.

组织胚胎学课件七年制英文医学班专用