Shin Hae Park, Kyoung Min Lee, Choun Ki Joo Department of Ophthalmology and Visual Science Korean Eye Tissue and Gene Ba

1. Shin Hae Park, Kyoung Min Lee, Choun Ki Joo Department of Ophthalmology and Visual Science Korean Eye Tissue and Gene Bank Related to Blindness The Catholic University of Korea Clinical Comparsion After Implantation of Three Different Aspheric IOLs Neither author has a financial or proprietary interest in any material or method mentioned.

2. Introduction • Advances in IOL technology using wavefront analysis induce the modifications of IOL surface to improve visual outcomes. • Aspheric IOLs has been reported to compensate the spherical aberration(SA) of the cornea and improve contrast sensitivity, which provides patients with better quality of vision compared with conventional IOLs. • The Tecnis 9003® IOL was designed to reduce to 0.27 ㎛ to correct corneal aberrations completely. • The Acrysof IQ® SN60WF IOLwas designed to produce negative SA of 0.20 ㎛. • The Adapt-AO ® IOLwas designed to be aberration free to maintain only the positive SA of cornea to be unchanged.

3. To compare the clinical results of implantation of 3 different types of aspheric IOLs – Tecnis Z9000®, Acrysof IQ®, ADAPT-AO®

4. 6 5 Sutureless technique In the bag IOL implantation 4 3 Phacoemulsification 2 About 5mm CCC diameter 1 3.00mm temporal clear corneal incision Topical anesthesia Materials and Methods Prospective and randomized study 90 eyes of 90 patients All cases were uncomplicated. Group A : 30 eyes implanted with Tecnis Z9003® (AMO, USA) Group B : 30 eyes implanted with AcrySof IQ® SN60WF (Alcon, USA) Group C : 30 eyes implanted with Adapt-AO® (Bausch & Lomb, USA)

5. Materials and Methods 1 Uncorrected visual acuity (UCVA) 2 Best corrected visual acuity (BCVA) Refractive error 3 Parameters 4 Sensitivity to glare achieved by ACV 5 Higher-order aberration 6 Contrast sensitivity 6 Parameters to Evaluate the clinical Outcome of 3 IOLs Postoperative 2 and 6 months Statisticalanalysis was done by Kruskall-Wallis test

6. Materials and Methods Preoperative characteristics *UCVA: uncorrected visual acuity *BCVA: best corrected visual acuity

7. Results – visual acuity * VA change : Postoperative BCVA – Preoperative BCVA

8. Results - refractive error *Refractive error (RE)= postoperative spherical equivalent – target refraction *SE : Spherical equivalent

9. Results – higher order aberrations

10. Results – ContrastSensitivity & Glare cpd ★ High photopic condition (100cd) Low photopic condition (5cd) ★ Under low and high photopic conditions, there was a statistically significant improvement in Tecnis Z9003® group at POD 6 months. 8/13 6/13 4/13 *Sensitivity to glare : decreased VA at photopic condition measured by ACV

11. Discussion • Negative SA of IOL affected the postoperative spherical aberrations. Postoperative spherical aberration was lowest in the eyes implanted with Tecnis Z9003 ® IOL. • 2. But, there were no significant differences in postoperative • BCVA, refractive error, glare among 3 different aspheric IOL groups. • There was a statistically significant improvement in Tecnis Z9003® • group at POD 6 months, under low and high photopic conditions. • 3. Three IOLs were different in IOL design and material of optic and haptic. • In addition to the spherical aberrations, these are factors to affect the • visual quality in each group. • 4. We cannot confirm that what level of SA can maximize the quality of • vision from this study. • 5. Further studies are needed to analyze the effect of preoperative value • of corneal SA to the quality of vision after implantation of different • aspheric IOLs.

12. Thank You for Your Attention ! ckjoo@catholic.ac.krhttp://cmc.cuk.ac.kr/lovis