1 / 22

Needs Assessment of Hepatitis C Testing, Treatment and Support Services:

Needs Assessment of Hepatitis C Testing, Treatment and Support Services: Survey of Laboratories in Scotland Undertaking Hepatitis C Testing. Survey objectives: to describe the existing provision of laboratory Hepatitis C testing services across Scotland

darci
Download Presentation

Needs Assessment of Hepatitis C Testing, Treatment and Support Services:

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Needs Assessment of Hepatitis C Testing, Treatment and Support Services: Survey of Laboratories in Scotland Undertaking Hepatitis C Testing

  2. Survey objectives: • to describe the existing provision of laboratory Hepatitis C testing services across Scotland • to examine the way in which individual laboratories operate with regard to Hepatitis C testing

  3. Survey response rate: Of 25 laboratories surveyed, 24 responses received 92% response rate Survey period: Data provided for period 1st Jan. to 31st Dec. 2006

  4. Hepatitis C antibody tests by NHS Board (where test performed), 2006 Not known 0 - 999 antibody tests 1000 - 3999 antibody tests 4000 - 7999 antibody tests 8000 - 11999 antibody tests 12000+ antibody tests N=61,700 HCV antibody test (cf. 40,000 in 2002/2003)

  5. Hepatitis C antibody tests by NHS Board (where test performed), 2006 Not known 0 - 999 antibody tests 1000 - 3999 antibody tests 4000 - 7999 antibody tests 8000 – 11999 antibody tests Grampian (13%) 12000+ antibody tests Greater Glasgow & Clyde (35%) Tayside (8%) Lothian (19%) Ayrshire & Arran (8%) N=61,700 HCV antibody tests

  6. Location of 14 Hepatitis C antibody testing laboratories* Not known 0 - 999 antibody tests 1000 - 3999 antibody tests 4000 - 7999 antibody tests 8000 – 11999 antibody tests 12000+ antibody tests Hepatitis C antibody testing laboratory Hepatitis C testing reference laboratory * 2 reference and 12 local laboratories N=61,700 HCV antibody tests

  7. Hepatitis C antibody tests in Scotland, 2006 Total HCV antibody tests (from laboratory survey): 61,700 Total HCV antibody positive tests (from laboratory survey): 3,141 New HCV antibody positive diagnoses (from National 1,520 Hepatitis C Diagnoses Database): 2.5% of all HCV antibody tests were new HCV diagnoses

  8. Source of all Hepatitis C antibody tests in Scotland, 2006 * Data on source of test provided by 2 reference laboratories and 10/12 local laboratories

  9. Source of all Hepatitis C antibody tests in Scotland, 2006 * Data on source of test provided by 2 reference laboratories and 10/12 local laboratories

  10. Source of all Hepatitis C antibody tests in Scotland, 2006 * Data on source of test provided by 2 reference laboratories and 10/12 local laboratories

  11. Hepatitis C PCR testing: • 3 laboratories undertake PCR testing (for diagnostic and monitoring purposes) - • a) West of Scotland Specialist Virology Centre (WSSVC) • b) East of Scotland Specialist Virology Centre (ESSVC) • c) Medical Microbiology Laboratory, Ninewells Hospital • In 2006, 5700 PCR tests performed; 70% at WSSVC, 22% at ESSVC, 8% at Ninewells Hospital

  12. Hepatitis C genotyping: • 2 specialist virology centres in Glasgow and Edinburgh perform HCV genotyping

  13. Hepatitis C genotyping: * Data extracted from National Hepatitis C Diagnoses Database

  14. Local laboratory testing/reporting algorithm following a negative antibody test result Local laboratories antibody testing 1st sample (n=11) 1st sample Negative test result Antibody result reported to source of request (n=11)

  15. Local laboratory testing algorithms following a positive antibody test result Local laboratories antibody testing 1st sample (n=11) 1st sample Positive test result * Responses are not mutually exclusive

  16. Local laboratory testing algorithms on second samples Local laboratories antibody testing 1st sample (n=11) 1st sample Positive test result 2nd sample Second sample requested (n=7) * Responses are not mutually exclusive

  17. Local laboratory reporting algorithms Local laboratories antibody testing 1st sample (n=11) Antibody result only reported to source of request (n=6) Negative test result Positive test result 1st sample Antibody result reported to source of request (n=11) Confirmed antibody and PCR results reported to source of request (n=8) PCR result only reported to source of request (n=2) No results reported to source of test request (n=1) 2nd sample Second sample requested (n=7) Antibody and PCR results reported to source of request (n=1) No further results reported to source of request (n=4) PCR result reported to source of request (n=2)

  18. Reference laboratory testing/reporting algorithms Reference laboratories antibody testing 1st sample (n=2) Negative test result Positive test result 1st sample Initial sample tested for PCR at ref. lab. (n=2) 2nd sample Second sample requested for confirmation testing (n=2) Confirmation PCR testing only at Ref. Lab. (n=1) Confirmation antibody and PCR testing at Ref. Lab. (n=1)

  19. Reference laboratory testing/reporting algorithms Reference laboratories antibody testing 1st sample (n=2) Negative test result Positive test result Result reported to source of request (n=2) 1st sample Antibody result reported to source of request (n=1) Initial sample tested for PCR at ref. lab. (n=2) PCR result reported to source of request (n=1) 2nd sample Second sample requested for confirmation testing (n=2) Confirmed antibody and PCR results reported to source of request (n=1) Confirmation PCR testing only at Ref. Lab. (n=1) Confirmation antibody and PCR testing at Ref. Lab. (n=1)

  20. Test result turn-around times* • Hepatitis C antibody test results • 12/14 laboratories provided data with median turn-around time of 15-21 days reported (range 1-3 days to 22-28 days) • * From date of initial sample at laboratory to date of reporting result to test request source

  21. Test result turn-around times ii) Hepatitis C PCR test results 11/14 laboratories provided data with median turn-around time of 15-21 days reported (range 8-14 days to 22-28 days) * From date of initial sample at laboratory to date of reporting result to test request source

  22. Summary: • At least one Hepatitis C antibody testing laboratory located in 10 of 14 NHS Board areas • In Scotland, approx. 50% increase in amount of Hepatitis C antibody testing undertaken from 2002/2003 to 2006 • Majority of PCR testing performed at WSSVC in Glasgow • Variety of testing and reporting algorithms applied at local laboratories following positive antibody result • Median turn-around time for antibody and PCR test results at local and reference laboratories 15-21 days

More Related