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Dive into the fundamental concepts of metabolism, including anabolism, catabolism, energy capture, oxidation, reduction, and redox reactions. Explore metabolic lifestyles, enzyme functions, inhibition, temperature, and pH influences. Learn about anaerobic and aerobic metabolism, glycolysis, the Krebs Cycle, and other metabolic processes.
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ESSENTIAL CONCEPTS OF METABOLISM CHAPTER 5
Metabolism • Anabolism • Catabolism
Energy Capture • Oxidation • Reduction • Redox NAD+ + e- -------> NADH Oxidized form Reduced form
Metabolic Lifestyles — Autotrophy • Photoautotroph • Chemoautotroph
Metabolic Lifestyles — Heterotrophy • Photoheterotroph • Chemoheterotroph
Enzymes • Role • Structure
Enzyme Sites • Active Site
Enzyme Inhibition • Competitive
Enzyme Inhibition • Non-competitive
Temperature Reaction Rate Influences
pH Reaction Rate Influences
Enzyme concentration Reactant concentration Product concentration Enzyme Reaction Rates
LeChatlier’s Principle and the BioChemical Pathway A + B C + D Want to go forward? Increase concentration of A + B or Decrease concentration of C + D
Anaerobic metabolism • Glycolysis
Anaerobic Pathways • Alternatives • Fermentation
Emden-Meyerhoff Standard glycolysis
Aerobic Metabolism • Krebs Cycle (aka. TCA cycle, citric acid cycle)
Anaerobic Respiration • Final electron acceptor differences
Fat Catabolism • Glycerol • Fatty Acids
Protein Catabolism • Deamination • Carbon skeleton usage
Protein anabolism(amino acid synthesis) Precursors off of Krebs cycle
Other Metabolic Processes • Photoheterotrophy (Rhodopseudomonas) • Light as energy carbohydrates as carbon source • Chemoautotrophy (Nitrobacter) HNO2 as energy CO2 as carbon source
Uses Of Energy • Biosynthesis • Membrane Transport Active transport/antiport • Movement ATP to drive flagella or cilia
Bioluminescence • Microbial Source