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Neoplasia

Neoplasia. Occupational factors Carcinogenic agent Cancer site. Arsenic and arsenic Lung,skin, compound hemangiosarcom Asbestos : Lung mesothelioma; Ethylene oxide : Leukemia

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Neoplasia

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  1. Neoplasia

  2. Occupational factors Carcinogenic agent Cancer site • Arsenic and arsenic Lung,skin, compound hemangiosarcom • Asbestos : Lung mesothelioma; • Ethylene oxide : Leukemia • Chromium compounds Lung carcinoma • Benzene : Leukemia, Hodgkin lymphoma • Vinyl chloride Angiosarcoma,liver • Cadmium and cadmium compounds : Prostate

  3. Neoplasia • Aparaneoplastic syndrom • A set ofsignsandsymptoms) that is the consequence ofcancerin the body, but unlikemass effect, is not due to the local presence of cancer cell • these phenomena are mediated byhumoralfactors (suashormonesorcytokines) secreted by tumor cells • or by animmune responseagainst thetumor

  4. Thanks

  5. Para neoplastic syndrom • Clinical Syndromes Major Forms of Underlying Cancer • Cushing syndrome Small cell carcinoma of lung • Pancreatic carcinoma • Inappropriate antidiuretic hormone secretion Small cell carcinoma of lung • Hypercalcemia Squamous cell carcinoma of lung • Hypoglycemia Fibrosarcoma carcinoma • Carcinoid syndrome Bronchial adenoma (carcinoid) • Polycythemia Renal carcinoma Cerebellar hemangioma Hepatocellular carcinoma • Myasthenia Bronchogenic carcinoma I • Acanthosis nigricans Gastric carcinoma • Lung carcinoma Uterine carcinoma • Dermatomyositis Bronchogenic, breast carcinoma • Hypertrophic osteoarthropathy bronchogenic carcinomas

  6. Grding and staging of tumor • Grading of a cancer is based on the degree of differentiation of the tumor cells and the number of mitoses within the • The staging of cancers is based on the size of the primary lesion, its extent of spread to regional lymph nodes, and the presence or absence of blood-borne metastases. tumor

  7. Markers Associated Cancers • Hormones • Human chorionic gonadotropin Trophoblastic tumors, nonseminomatous testicular tumors • Calcitonin • Medullary carcinoma of thyroid • -Fetoprotein Liver cell cancer, nonseminomatous germ cell tumors of testis • Carcinoembryonic antigen Carcinomas of the colon, pancreas, lung, stomach, and heart • Prostatic acid phosphatase Prostate cancer • Prostate-specific antigen and prostate-specific membrane antigen Prostate cancer • CA-125 Ovarian cancer

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