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Pharmaceutical Process Development and ACS Journal Editorship; not a typical career in chemistry??.
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American Chemical Society Pharmaceutical Process Development and ACS Journal Editorship; not a typical career in chemistry?? Jaan Pesti.Principal Scientist Associate EditorBristol-Myers Squibb Co American Chem SocProcess Res & Dev Organic Process R & DNew Brunswick, NJ Yardley, PA
Route to become a process chemist; the early years • Bachelor of Arts • Long Island University – Brooklyn Center • Pharmacy • Organic chemistry • Joined ACS in 1974 • C & E News - eye on what is happening • Job surveys • Belong to the guild • Ph.D in Organic Chemistry • Columbia University • What if things don’t work out? Be flexible! • Synthetic chemistry • Enjoyed ‘writing up,’ first clue for my future
Route to become a process chemist; the early years • Post-doctoral studies • University of California at Berkeley • Synthetic organic chemistry • Supervision of undergraduate • Make connections • How to ‘sell’ yourself
Where have I been since school?? • Worked for four companies • Dupont Chemical Co • Dupont Merck • Dupont Pharmaceuticals • Bristol-Myers Squibb • Moved five times • Dupont Experimental Station • Dupont Chambers Works • X Station again • Chambers Works again • BMS Princeton site • BMS New Brunswick site • But have always been primarily a bench chemist! • Know what you are!
What do I do at Bristol Myers Squibb?? • figure out how to scale up processes for new pharmaceutical agents. - safety - cost - speed - future • organize and prepare multikilogram batches for a variety of studies, including clinical. • instruct and oversee outside vendor preparations. • anticipate future needs. • preparation for regulatory documents, which leads to……………………..
Now for something completely different Associate Editorship of Org Process Res & Dev background • take control of one’s own career • started publishing & presenting in 1998 • ACS Nat mtgs, ACS journals • became OPRD reviewer in 2006 • joined OPRD Editorial Advisory Board in 2007 • became OPRDAssoc. Editor in 2008
What is the role of an Assoc. Editor?? • assign manuscripts for review • oversee review process • review all manuscripts for content, style, etc • make decision to accept, reject or revise • make final acceptance • recruit talent for OPRD • market OPRD • provide guidance for future direction of journal • in general, whatever will improve the service of OPRD to our readers
Secrets to being published! • first, do something worth publishing • what is the theme of your publication • feel free to ask an Assoc Editor • before you start writing, what journal are you targeting. • get a fast first draft down on paper • then rewrite, rewrite, rewrite, rewrite • but write in good English • write dynamically and avoid the passive voice • check the ACS style guide • ask a colleague to critique your manuscript • be accurate • avoid silly mistakes • cite OPRD frequently