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1. AMERICAN POISON CENTERSEmergency CarePreventionToxicosurveillance Edward P. Krenzelok, PharmD, FAACT, DABAT
Director
Pittsburgh Poison Center
Professor of Pharmacy and Pediatrics
University of Pittsburgh
AAPCC Board of Directors
2. OBJECTIVES PROVIDE A HISTORICAL PERSPECTIVE
DESCRIBE THE CONTEMPORARY CAPABILITIES OF POISON CENTERS Emergency Care Poison Prevention
DISCUSS THE NATIONAL POISON DATA SYSTEM (NPDS) Data Collection Toxicosurveillance
3. THE EVOLUTION OF US POISON CENTERS 1940-50’s800-1400 home poisoning fatalities/yr
33% = < 4 yr of age
1953First Poison Center
1958AAPCC
1970Poison Prevention Packaging Act
1978~800 Poison Centers
1983Toxic Exposure Surveillance System
2002Nat’l Toll Free No.1-800-222-1222
200761 Centers24/7 Service
4. 200761 US Poison Centers
5. US POISON CENTERSScope of Practice
6. US POISON CENTER ACCESSCommon Telephone Number
7. US POISON CENTERSEmergency Care UNIFORM QUALITY STANDARDSAAPCC Certified Regional Centers
24/7 Service
2006 Statistics4,033,279 Calls
8. US POISON CENTERSTypes of Calls-2006 EXPOSURESHuman-2,403,539 Animal-128,353
INFORMATIONDrug ID-948,055Drug Info-176,746Prevention-44,489
9. WHO CALLS POISON CENTERS? PUBLIC
PHYSICIANS
NURSES
PSAP’s
PHARMACISTS
PARAMEDICS
VETERINARIANS
URGI-CARE CTRS
HEALTH DEPT’S OCCUP MED MD
POLICE
FIRE SERVICES
PRISON OFFICIALS
CORONERS
ATTORNEYS
INDUSTRY
SCHOOLS
GOV’T
10. WHO CALLS POISON CENTERS?
11. POISON CENTER STAFFING
12. RESOURCES Expert StaffSpecialists in Poison InformationClinical Toxicologists
Consultants
Reference Texts
Online Resources-Micromedex
Literature Files
Internet Resources
Poison Center Treatment Guidelines
13. THE POISON CENTER PRODUCT
14. ACETAMINOPHEN EXPOSURE
15. POISON PREVENTION EDUCATIONThe Key To Success AAPCC CERTIFICATION STDEducation is Mandatory Lay Public
Medical Professionals
POISON CENTER AWARENESS
16. NATIONAL POISON DATA SYSTEMNPDS FORMERLY = TESS
DATA COLLECTION
RETROSPECTIVE ANALYSIS
REALTIME TOXICOSURVEILLANCE
17. Poison centers create a medical record as they respond to the poisoning emergency….
20. NPDS SURVEILLANCERetrospective Analysis
21. NPDS SURVEILLANCERealtime SPIs DOCUMENT LOCALLY
AUTOUPLOAD4-6 Min Lag TimeLocal Nat’l Surveillance Servers
SURVEILLANCE TEAMMine Data 24/7 Increased Activity Unusual Patterns Syndromic Surveillance Sentinel Events
100% COVERAGE-US, PR, Territories
22. TOXICOSURVEILLANCEExamples Look for early indicators of outbreaks
Rapidly detect and report chemical or biological events.
Continuously search for patterns suggesting covert chemical or biological events.
Identify chemicals, products, environmental agents, and consumer products with potential public health significance.
23. ID SUBSTANCE ABUSE TRENDS February 7, 2001M360 Hydrocodone 7.5 mg/APAP 750 mg Vicodin ES ‘Generic’
February-March, 2001222 ID Requests
PGH DRUG DIVERSION TASK FORCESupplied ZipcodesDrug Diversion Source Identified
24. DISEASE SURVEILLANCE AND NONPRESCRIPTION MEDICATION SALES CAN PREDICT INCREASES IN POISON EXPOSURE CALLS
26. Chem/Bio Terrorism and Poison CentersAnthrax Calls 6/2000 through 6/2002
27. SALMONELLA TAINTED PEANUT BUTTER
28. AAPCC HAND SANITIZER DATA
29. RESEARCH MEDICAL RECORD REVIEW
PROSPECTIVE
DATABASE ANALYSIS
EVIDENCE-BASED REVIEWS
BASIC SCIENCE