Announcements

1. Announcements • Turn in your “I am a _________ cell” information with name on back side and definition of “homeostasis.” • Personal info (voluntary) due Friday • Group pictures in lab this week • Switch to Tuesday Morning Lab? • Community of Scholars Research Symposium • Saturday Sept 11 from 9- noon • 10 weeks paid research on topic of your choosing! • Summer 2011?

2. 1QQ # 1 Name on top edge, back side of paper Answer on blank side of paper. Answer one of the following: • The 200+ cell types in the human body can be classified into one of 4 cell types or tissue types. List 3 of the 4 types. • List as many items that you can think of that are measured and reported in a CBC (complete blood count.) • Why are CBCs so important to physicians and their patients?

3. A Taxonomy of Cognitive Skills for Developing Student Assignments and Assessments* *SC SDE (Pat Mohr). Adapted from Lorin W. Anderson, David R. Krathwohl et al (Eds.) A Taxonomy for Learning, Teaching, and Assessing: A Revision of Bloom’s Taxonomy of Educational Objectives 2001; modified by Ellen Goldey, Wofford College, to incorporate “Biology in Bloom,” Crowe et al., 2008, CBE – Life Sci Edu., 7: 368-381. **HOCS = higher order cognitive skills, LOCS = lower order cognitive skills.

4. The body: A society of interdependent cells, each type with its own needs and contributions.

5. The Human Body:A Society of Cells • Imagine you are a cell. Ask yourself: • How did I get here?  • What do I do for myself? (What are my special characteristics and functions?)  • What do I do for the person in whom I reside? (What are my contributions to the whole organism? To homeostasis?)  • What do I need simply to survive? • What do the other cells provide for me that I cannot obtain alone? • What governs my actions?  • How long will I live? • Can I be replaced? If so, how? • What would happen to the organism if I along with all the other cells of my type were to fail to function properly?

6. O2 pH CO2 Temp, [glucose], [Na+],[K+],[Ca++],amino acids Nucleic acids

7. Cell Membrane: selectively permeable Capillaries: highly permeable except to proteins

8. Homeostasis: • The relative constancy of the internal environment • Steady state vs. equilibrium BeggarThessaloniki, Greece

9. Homeostasis: • The relative constancy of the internal environment • Steady state vs. equilibrium Street vendorThessaloniki, Greece

10. Homeostasis: • The relative constancy of the internal environment • Steady state vs. equilibrium San womanKalahari Desert, Botswana

11. Homeostasis: Camp’s Bay Beach, Cape Town, South Africa

12. Homeostasis: Phillip cooling off in waterfall, Vietnam

13. ~37oC

14. Homeostasis • Regulated via reflex arcs and naturally maintained by the process of negative feedback • Measurement • Which physiological variables? • Averages and ranges

15. Fig. 01.08 Diurnal cycles Awake Awake Sleep Sleep Major point: Set points are not absolute!

16. Thermoregulation An example of homeostasis bynegative feedback.

17. The Challenge: # 1: Melt these 7 ice cubes as fast as possible. How to do it? # 2: Make these 7 ice cubes last as long as possible? How to do it? These are non-living objects: heat exchanges with the environment but they don’t generate heat from metabolism as living things do!

18. ~37oC • Conduction • Convection • Evaporation • Radiation Metabolism generates heat. Metabolism is variable! In steady state: Heat gain = Heat loss

19. Modes of Heat Exchange: Conduction Convection Radiation Evaporation ~37oC

20. Modes of Heat Exchange: Conduction Convection Radiation Evaporation ~37oC

21. Modes of Heat Exchange: Conduction Convection Radiation Evaporation ~37oC

22. http://www.nws.noaa.gov/os/windchill/windchillglossary.shtml