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Immune System Project : CD28

Immune System Project : CD28. BY: Wells Powell & Tamia Johnson.

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Immune System Project : CD28

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  1. Immune System Project :CD28 BY: Wells Powell & Tamia Johnson

  2. CD28: Resting and Activation of a T-cellCD28 T-cells appear relatively, through A variety of mechanisms significantly impacting,And significantly contributing, to the immune Defect, that is characterized of the elderly Frequently, expanded and constrained, to theAdaptive immune system by completing for Available space, IN THIS PLACE!!!

  3. What Is it!!!! CD28 signaling promotes T cell activation and upregulation of CTLA-4. Blockade of CD28 signal with CTLA-4 I or B7 antibodies inhibits T cell activation. CTLA-4 signaling down-regulates T cell responses. Inhibition of this signal with anti-CTLA-4 maintains an active immune responses. Resting T cells express TCR and CD28; activated T cells express CD28, CTLA-4, and TCR; and APCs express MHC plus peptide and B7.

  4. Diseases have been found through this cell • Among various inflammatory syndromes • Including HIV wells • And chronic disease in these windows Disease related to it!

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