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Dr Imtiaz M Qazi. Deep Neck Infections. Introduction. “Pus in the neck calls for the surgeon’s best judgement , his best skill and often for all of his courage” …… Mosher. Problems. Complex Anatomy: precise localization difficult
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Dr Imtiaz M Qazi Deep Neck Infections
Introduction “Pus in the neck calls for the surgeon’s best judgement, his best skill and often for all of his courage” …… Mosher
Problems • Complex Anatomy: precise localization difficult • Deep Location: difficult to palpate, impossible to visualize • Access: intervening neurovascular & soft tissue structures at risk • Proximity: vital structures • Communication: spread to adjacent space, large area of neck
Deep Neck Spaces And Infections • Anatomy of the Cervical Fascia • Anatomy of the Deep Neck Spaces • Deep Neck Space Infections
Cervical Fascia • Superficial Cervical Fascia • Deep Cervical Fascia • Encircle H&N and attached to clavicle and zygomatic arch • Contain plastysma m. and external jugular v. • Marginal mandibular br. of Facial n. lies just deep • to superficial cervical fascia
Deep Cervical fascia • Superficial Layer • Middle Layer • Deep Layer
Superficial Layer DCF Investing/ Enveloping layer Muscles • Sternocleidomastoid • Trapezius Glands • Submandibular • Parotid Space • Suprasternal space of Burns
Middle Layer DCF Muscular Division • Infrahyoid Strap Muscles Visceral Division • Pharynx, Larynx, • Esophagus, Trachea, • Thyroid Buccopharyngeal Fascia
Deep Layer DCF Alar Layer • Posterior to visceral layer of middle fascia • Anterior to prevertebra layer Prevertebral Layer • Vertebral bodies • Deep muscles of the neck
Carotid Sheath • Formed by all three layers of deep fascia • Contains carotid artery, internal jugular vein, and vagus nerve • “Lincoln’s Highway”
Deep Neck Spaces And Infections • Anatomy of the Cervical Fascia • Anatomy of the Deep Neck Spaces • Deep Neck Space Infections
Deep Neck Spaces • Described in relation to the hyoid • Entire length of the neck • 1.Retropharyngeal Space • 2. Danger Space • 3. Prevertebral Space • 4. Visceral Vascular (Carotid) Space • Suprahyoid • 5. Submandibular Space • 6. ParaPharyngeal Space • 7. Masticator/Temporal Space • 8. Parotid Space • 9. Peritonsillar Space • Infrahyoid • 10. Anterior Visceral Space
Deep Neck Spaces • Entire Length of Neck: • 1. Prevertebral Space • Anterior border is prevertebral • fascia, posterior border is vertebral • bodies and deep neck muscles. • Extends along entire length • of vertebral column from skull base to • coccyx • Contains very compact tissue • Spread is therefore slow
Deep Neck Spaces • Entire Length of Neck: • 2. Danger Space • Anterior border is alar layer • of deep fascia, posterior border • is prevertebral layer. • Extends from skull through • posterior mediastinum to • diaphragm. • Contains very loose • areolar tissue offering • little resistance to the spread • of infection to the mediastinum
Deep Neck Spaces • Entire Length of Neck: • 3. Retropharyngeal • Space • Posterior to pharynx • and esophagus, between visceral div • of middle layer and alar div of deep • layer • Extends from skull base to T1-T2 • Midline raphe • Two chains of nodes on either side of the • midline
Deep Neck Spaces • Infrahyoid • 3. Anterior Visceral • Space • Middle layer of deep fascia • Contains thyroid, • trachea, esophagus • Extends from thyroid • cartilage into superior • mediastinum
Deep Neck Spaces • Suprahyoid: • 4. Para Pharyngeal Space • Superior: skull base • Inferior: hyoid • Prestyloid • IMA • Inf Alveolar N • Auriculotemporal N • Connective tissue, fat & nodes • Poststyloid • Carotid sheath • Cranial nerves IX, X, XII • Sympathetic chain
Deep Neck Spaces • Suprahyoid: • 5. Submandibular Space • Anterior/Lateral: mandible • Superior: oral mucosa • Inferior: superficial layer of deep fascia • Posterior/Inferior: hyoid • Supramylohyoid portion • Sublingual gland • Hypoglossal and lingual • nerves • Portion of Submandibular gland • Inframylohyoid portion • Submandibular gland • Wharton’s duct • Anterior bellies of digastrics
Deep Neck Spaces • Suprahyoid: • 6. Masticator and • Temporal Spaces • Bounded by the • superficial layer of deep • cervical fascia • Contains masseter, pterygoids, • temporalis, ramus and • posterior portions of the body • of mandible, inferior alveolar • vessels and nerves
Deep Neck Spaces • Suprahyoid: • 7. Parotid Space • Superficial layer • of deep fascia • Dense septa from • capsule into gland • Relationship • to parapharyngeal space
Deep Neck Spaces Submandibular Temporal Masticator Peritonsillar Lateral Pharyngeal Parotid Vascular Retropharyngeal Danger Network of patterns of infectious extension Prevertebral Anterior Visceral Mediastinum
Deep Neck Spaces And Infections • Anatomy of the Cervical Fascia • Anatomy of the Deep Neck Spaces • Deep Neck Space Infections
Deep Neck Space Infections • Before antibiotics - 70% by tonsillar and pharyngeal sources • Most common cause in adults: Odontogenic, IVDA • Most common cause in paeds: Tonsillar, URTI • Others: salivary gland, trauma, FB, instrumentation, local or superficial source • 22% without cause 1. Tom MB, Rice DH: Presentation and management of neck abscesses: a retrospective analysis, Laryngoscope 98:877, 1988
Etiology • Tonsillar and pharyngeal infection • Dental infection • Oral surgical procedures • Trauma of upper aerodigestivetract • Cervical lymphadenitis • Retropharyngeal lymphadenitis • Pott’s disease • Sialadenitis • Bezold’s abscess • Infection of congenital cyst and fistula • Intravenous drug abuse • Necrosis/suppuration of a malignant cervical LN/mass
Bacteriology • Most abscesses contain mixed bacterial flora Aerobes: Streptococci β-hemolytic (Strep pyogehes), Strept. Viridans, Strep pneumoniae Staphylococci, Neisseria, Klebsiella, Haemophilus (Decresed role of b-hemolytic Streptococci) Anaerobes: Bacteroides, Peptostreptococcus, fusobacterium Less common: Pseudomonas, E.coli & H. infuenzae • Anaerobes are understimated (>35%) widespread antibiotic use prior to collection of cultures poor sample collection techniques fragility of anaerobes • Anaerobes produce b-lactamase
Signs and Symptoms • Fever, elevated WBC count, & tenderness • Asymmetry of neck & asstd neck mass/LN • Medial displacement of tonsil or lateral pharyngeal wall • Trismus • Torticollis • Fluctuation usually not palpable • Neural deficit: Horner’s Synd, Hoarseness • Spiking fever: IJV Thrombosis, Septic embolus • Airway obstruction
Treatment • Airway protection • Antibiotic therapy • Surgical drainage
Treatment • Empirical Treatment First-line Clindamycin 600-900mg tid (+/- cefuroxime 0.75-1.5gr tid) or Penicillin G 24 million units/day + Metronidazole 1gr bid Alternatives AMX/CL 1.5-3gr qid or PIP/TZ 2.25gr qid - 4.5 gr tid
Imaging • Lateral neck plain film • Screening exam—mainly for retropharyngeal and pretracheal spaces • Normal: 7mm at C-2, 14mm at C-6 for kids, 22mm at C-6 for adults • Technique dependent • Extension • Inspiration • Nagy, et al • Sensitivity 83%, compared to CT 100%
Imaging • Ultrasound (USG) • Advantages • Avoids radiation • Portable • Disadvantages • Not widely accepted • Operator dependent • Inferior anatomic detail • Uses • Following infection during therapy • Image guided aspiration
Imaging • Contrast enhanced CT • Advantages • Quick, easy • Widely available • Familiarity • Superior anatomic detail • Differentiate abscess and cellulitis • Disadvantages • Ionizing radiation • Allergenic contrast agent • Soft tissue detail • Artifact
Imaging • MRI • Advantages • No radiation • Safer contrast agent • Better soft tissue detail • Imaging in multiple planes • No artifact by dental fillings • Disadvantages • Increased cost • Increased exam time • Dependent on patient cooperation • Availability Munoz, et al: MRI vs. CT
Management History + Physical examination Culture, IV antibiotics, Airway control, Chest RX CT cellulitis large abscess small abscess needle aspiration for culture & drainage W&W 24-48h complications? improvement? No Yes surgical incision and drainage Continue AB
Complications • Airway obstruction • Internal jugular vein thrombosis • Cavernous sinus thrombosis • Neurologic deficit – Horner’s, hoarseness • Erosion of carotid artery • Osteomyelitis of the mandible • Osteomyelitis of the spine • Mediastinitis • Pulmonary edema • Pericarditis • Aspiration • Sepsis
Para Pharyngeal Abscess • Most common cause : Peritonsillar infection • Typical finding 1.Trismus 2.Angle mandible swelling 3. Medial displacement of lateral pharyngeal wall Others : fever, limit neck motion, neurologic deficit (C.N 9,10,12,Horner’s syndrome)
Para Pharyngeal Abscess Treatment • Evaluate and maintain airway & fluid hydration • Parenteral antibiotic high dose 24-48 hrs. • If not improve, consider surgical drainage Surgical drainage • Intraoral approch (for peritonillar abscess only) 2. External approach -transverse submandibular incision -T. shape incision (Mosher)
Retro Pharyngeal Abscess Clinical feature • In children irritability, neck rigidity, fever, drooling, muffled cry, airway compromise • In adult fever, sore throat, odynophagia, neck tenderness, dyspnoea
Retropharyngeal Abscess Investigation • Lateral neck film - C2 > 7 mm. both children and adult - C7 > 14 mm. in children > 22 mm. in adult. • Chest film - detection of mediastinitis
Retropharyngeal Abscess Treatment Surgical drainage • Intraoral drainage -Lesion confined in RP space esp.child • External drainage (Dean) -Lesion beyond pharyngeal level -Airway compromise -Involve other deep neck spaces
Quinsy • Peritonsillar Space • Fever, malaise • Dysphagia, odynophagia • “Hot-potato” voice, trismus, bulging of superior tonsil pole and soft palate, deviation of uvula • Cause—extension from tonsillitis
Parotid Space Infection • Most common cause : Bacterial retrograde from oral cavity Clinical feature • high fever, weakness, mark swelling and tenderness of parotid gland, fluctuation,pusat stensen’s duct
Ludwig’s Angina Ludwig’s angina is characterized by rapidly spreading cellulitis / infection of the sublingual and submaxillary spaces with associated swelling of the submental region, tongue and floor of the mouth, secondary to dental infection.
Ludwig’s Angina Grodinsky’s criteria (1939): 1.A cellulitis, not an abscess of submandibular space 2. The cellulitis involves all the sublingual and bilateral submaxillary spaces 3. The cellulitis produces a serosanguineous putrid infiltration but very little or no frank pus 4. Fascia, muscle, connective tissue involvement, sparing glands 5. The cellulitis is spread by continuity and not by lymphatics