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CVM faculty on Bacterial Infectious Diseases

CVM faculty on Bacterial Infectious Diseases. Yinduo Ji Department of Veterinary Biomedical Sciences. Faculty Expertise. Epidemiology Bacterial pathogenesis Mechanism of antibiotic resistance Microbiome / metagenomics Vaccine development Novel antibacterial discovery Diagnosis.

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CVM faculty on Bacterial Infectious Diseases

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  1. CVM faculty on Bacterial Infectious Diseases Yinduo Ji Department of Veterinary Biomedical Sciences

  2. Faculty Expertise • Epidemiology • Bacterial pathogenesis • Mechanism of antibiotic resistance • Microbiome/metagenomics • Vaccine development • Novel antibacterial discovery • Diagnosis

  3. Bacterial pathogenesis • Gram-negative pathogens: • Escherichia coli, Salmonella enterica, Lawsonia intracellularis, Haemophilus parasuis • Gram-positive pathogens: • Staphylococcus aureus, including MRSA, Streptococcus suits, Mycobacterium avium subsp. paratuberculosis (MAP) and M. bovis • Microbe-host interaction • Microbe-microbe interactions

  4. Approaches • Genetics • Genomics • Metagenomics • Proteomics • System biology • Cell culture • Animal Models

  5. Current projects • Identification and validation of novel targets in vitro and in vivo • Development of high throughput screening of antibacterial inhibitor • Whole-cell screening of novel antibacterial small molecules • Identification of mode of action for novel antibacterial agents • Investigation of molecular mechanisms of antibiotic resistance • Microbial population shifts in response to antibacterials

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