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Epidemiology of Туре 1 Diabetes Mellitus (T1DM) among children of Novosibirsk City, Russia

Evaluate T1DM incidence trends among children under 15 from 1980 to 2006 in Novosibirsk City, Russia, analyzing age, sex, and seasonality patterns. Results show increasing T1DM incidence, higher among older children, with peaks in March and October.

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Epidemiology of Туре 1 Diabetes Mellitus (T1DM) among children of Novosibirsk City, Russia

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  1. Epidemiology ofТуре 1 Diabetes Mellitus (T1DM) among children of Novosibirsk City, Russia Sazonova O.V., Simonova G.I., Shubnikov E.V., Galenok V.A., Vaskina E.A., Nikiforov O.A., Akopova A.G., Choubnikova J.M., Nikitin Yu.P. Novosibirsk State Medical University, Institute of Internal Medicine, City Diabetes center, Center for Endocrinology “SibDiab”, Novosibirsk, Russia

  2. Novosibirsk is big industrial center in Western Siberia

  3. Objective:To evaluate time trends of T1DM incidence among children under age 15 from 1980 to 2006 years in Novosibirsk City according data of population registries.

  4. The goals of Investigation: • To find out time trends of T1DM incidence among 0-14 years old children in Novosibirsk City from 1980 to 2006 years. • To estimate age-sex peculiarities of T1DM incidence in Novosibirsk City. • To estimate seasonality of manifestation of T1DM among children during the years 2000-2006.

  5. Methods:The epidemiologic survey in Novosibirsk City has been conducted according to standards of WHO program “Diamond” (1980-2000) and Russian National Registry of DM (from 2000). Two sources of information have been used including data from Novosibirsk’s City hospitals and data from Novosibirsk’s City children endocrinologists. There were four criteria for inclusion – DM diagnosis, manifestation before 15 birthday, Novosibirsk City’ citizenship for at least 1 year and insulin implementation as initial treatment .The number of cases for 2000 year, estimated by both methods independently, was identical.

  6. RESULTS

  7. The time trends of T1DM incidence among children under age 15 from 1980 to 2006 years in Novosibirsk City.

  8. There is similar patterns of incidence among children of Novosibirsk City, Moscow City and Russia in whole

  9. 15 10 5 1980-1989 1990-1999 2000-2006 The mean T1DM incidence was significantly higherin 2000-2006 study period: 95%CI (7,1-9,9) 95%CI (4,1-6,6) 95%CI (13,4-18,5)

  10. There is significant growth of incidence among both sexes

  11. The mean T1DM incidence among children from 0-4 age group was lower compare to 5-9and 10-14 age groups.

  12. The mean T1DM incidence among children of 0-4 years old, Novosibirsk, Russia 95% CI (4,3-13,7) 95% CI (5,4-8,9) 95% CI (1,3-3,8)

  13. The mean T1DM incidence among children of5-9 years old, Novosibirsk, Russia 95% CI (15,7-25,4) 95% CI (3,7-7,1) 95% CI (7,0-12,1)

  14. The mean T1DM incidence among children of10-14 years old, Novosibirsk, Russia 95% CI (10,1-26,6) 95% CI (6,4-10,4) 95% CI (5,8-11,6)

  15. Trends and the Prognosis of Incidence growth in different age groups among Novosibirsk City children.

  16. Seasonality in manifestation of T1DM cases among children 0-14 years during 2000-2006 years with picks in March and October

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