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Case presented by Dr Moriarty

Case presented by Dr Moriarty. 83 yo woman: PMH – 40 yr h/o IBD on active meds, but non-compliant with f/u colonoscopies 2010: Increased bleeding and abdominal pressure PET/CT = tumor from distal sigmoid to anal verge plus deep lymph nodes Biopsy = adenocarcinoma of the rectum

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Case presented by Dr Moriarty

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  1. Case presented byDr Moriarty • 83 yo woman: PMH – 40 yr h/o IBD on active meds, but non-compliant with f/u colonoscopies • 2010: Increased bleeding and abdominal pressure • PET/CT = tumor from distal sigmoid to anal verge plus deep lymph nodes • Biopsy = adenocarcinoma of the rectum • Consultation to discuss tx for locally advanced rectal CA with known IBD

  2. Phase III Trial Assessing Bevacizumab in Stages II and III Carcinoma of the Colon: Results of NSABP Protocol C-08 Allegra CJ et al. J Clin Oncol 2011; 1(29); 11-16 Lessons From the Adjuvant Bevacizumab Trial on Colon Cancer: What Next? Eric Van Cutsem et al. J Clin Oncol 2011 1(29); 1-4

  3. AVANT: Results from a Randomized, Three-Arm Multinational Phase III Study to Investigate Bevacizumab with Either XELOX or FOLFOX4 vs FOLFOX4 Alone as Adjuvant Treatment for Colon Cancer De Gramont A et al. Proc GICancersSymposium 2011;Abstract 362.

  4. Case presented byDr Moriarty • 83 yo woman: PMH – 40 yr h/o IBD on active meds, but non-compliant with f/u colonoscopies • 2010: Increased bleeding and abdominal pressure • PET/CT = tumor from distal sigmoid to anal verge plus deep lymph nodes • Biopsy = adenocarcinoma of the rectum • Consultation to discuss tx for locally advanced rectal CA with known IBD

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