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Exploring the MAP web-site. Shuchismita Dutta March 2006. The Molecular Anatomy Project. What is it? Integrated view of a biological system Who is it for? General users, educators, students and researchers. How does it work? Select an organ system to explore
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Exploring the MAP web-site Shuchismita Dutta March 2006
The Molecular Anatomy Project • What is it? • Integrated view of a biological system • Who is it for? • General users, educators, students and researchers. • How does it work? • Select an organ system to explore • Read narrative version of how it functions • Browse through brief accounts of the molecules that participate in the functioning (enzyme, hormone etc.) • Why is it important? • Provides integrated view • Comparison of molecules with similar sources and/or functions • Gateway into PDB for users not familiar with structural biology or with the specific organ system
The human digestive system • Where: Anatomical view of digestion • organ system, organ, cell • How: Physiological view of digestion • membrane potentials, muscle contractions in peristalsis • hormone control, feedback control • What: Biochemical view of digestion • digestion of proteins, carbohydrates, lipids by enzymes, cofactors • What if: Common diseases • Online Mendelian Inheritance in Man (OMIM) • Integrated molecular view of digestion in MAP
Where does it happen? Organ System Cells Organ http://cwx.prenhall.com/bookbind/pubbooks/silverthorn2/medialib/Image_Bank/html/custom20.html
How does it happen? Membrane Potential Muscle contraction http://cwx.prenhall.com/bookbind/pubbooks/silverthorn2/medialib/Image_Bank/html/custom20.html
What happens in digestion? Digestion of protein Digestion of carbohydrates http://cwx.prenhall.com/bookbind/pubbooks/silverthorn2/medialib/Image_Bank/html/custom20.html
What if? Search for diseases related to stomach
Content Management System (CMS) Author 2 Author 3 Author 1 WWW Author 4 http://www.steptwo.com.au/papers/kmc_evaluate/
The MAP and mapdev sites • http://map.rutgers.edu/ • http://mapdev.rutgers.edu/