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Hormonal and Surgical Contraception. Tod C. Aeby, MD John A. Burns School of Medicine Department of Obstetrics, Gynecology and Women’s Health. Learning Objectives. Combination Oral Contraceptive Pills Progestin Only Contraceptive Pills Injections and Implants Patches and Rings
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Hormonal and Surgical Contraception Tod C. Aeby, MD John A. Burns School of Medicine Department of Obstetrics, Gynecology and Women’s Health
Learning Objectives • Combination Oral Contraceptive Pills • Progestin Only Contraceptive Pills • Injections and Implants • Patches and Rings • Emergency Contraception • Surgical Sterilization
Average Failure Rates (%) During the First Year of Use of a Contraceptive Method Methods Average NORPLANT SYSTEM 0.05 Male sterilization 0.15 Female sterilization 0.5 Depo-Provera (injectable progestogen) 0.3 Oral contraceptives 5 IUD Progesterone 2.0 Copper T 380A 0.8 Condom (male) without spermicide 14 (female) without spermicide 21 Cervical cap Never given birth 20 Given birth 40 Diaphragm with spermicide 20 Spermicides alone 26 Periodic abstinence (all methods) 25 Withdrawal 19 No contraception (planned pregnancy) 85
Combination Oral Contraceptive Pills • Components • Mechanisms of Action • Health Risks • Non-contraceptive Benefits
Components through time • Ethinyl Estradiol • Norethindrone • Levonorgestrel • Desogestrel • Norgestimate • Gestodene
Mechanism of Action • Inhibition of ovulation • Cervical mucus changes • Endometrial changes • Tubal motility changes
Advantages • Reliable • Convenient • Discreet
High Dose OCP Risk • Heart Disease • Thromboembolic Disease (blood clots) • Glucose intolerance (diabetes) • Liver cysts • Breast and Cervix Cancer?
Modern Health Risks • Slight increase in blood clot formation • Gallbladder disease • Heart disease in smokers over age 35
Non- contraceptive Benefits • Menstrual regulation • Protects against cancer • Improves acne and hirsutism • Decreased breast and ovarian cysts • Better sex
Non- contraceptive side effects • Nausea • Menstrual changes (spotting, amenorrhea) • ??weight changes?? • Minimal impact on lactation
Progestin only Pill • “The Mini Pill” • Less cycle control (often periods stop with time) • Slightly higher failure rate • Fewer health risks
Depo Provera • 150 mg shot every 12 weeks • Progestin only side effect profile • Duration unpredictable
Norplant • Levonorgesterel • Surgically implanted and removed • Good for 5 years • Same side effects as other progestin only methods
Emergency Contraception • Reduces risk of pregnancy after unprotected intercourse by at least 74% • No medical contraindication (except pregnancy) • Must be within 120 hours • 2 doses, 12 hours apart
Preven: estrogen + progestin • Plan B: progestin only
IUDs Mirena Progestasert Paragard
Male Hormonal Contraception? • Most methods suppress LH/FSH and then replace testosterone • GnRH or progestin • Implants, shots, pills • Inject vas deferens with polymer • Anti-sperm compounds • Anti-sperm vaccine
Male Surgical Sterilization: Vasectomy • Outpatient surgical procedure • .1% failure rate • No impact on sexual functioning • No known long term health risks
Female Surgical Sterilization • Electrocautery • Silastic band • Cut and tie • Clip • Springs
Average Failure Rates (%) During the First Year of Use of a Contraceptive Method Methods Average NORPLANT SYSTEM 0.05 Male sterilization 0.15 Female sterilization 0.5 Depo-Provera (injectable progestogen) 0.3 Oral contraceptives 5 IUD Progesterone 2.0 Copper T 380A 0.8 Condom (male) without spermicide 14 (female) without spermicide 21 Cervical cap Never given birth 20 Given birth 40 Diaphragm with spermicide 20 Spermicides alone 26 Periodic abstinence (all methods) 25 Withdrawal 19 No contraception (planned pregnancy) 85