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THC: tetrahydrocannabinol. MALI BOWERS PHYSIOLOGY FALL 17 THC PRESENTATION. WHAT IS THC?. psychoactive organic compound ( sī’kōˈak’tiv / adj. / affects the CNS) Molecular formula: C 21 H 30 O 2 (delta-9-THC) Molecular weight: 314.4 g/mol. A.K.A Weed Pot Cannabis Ganga Grass
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THC: tetrahydrocannabinol MALI BOWERS PHYSIOLOGY FALL 17 THC PRESENTATION
WHAT IS THC? • psychoactiveorganic compound • (sī’kōˈak’tiv / adj./ affects the CNS) • Molecular formula: C21H30O2 (delta-9-THC) • Molecular weight: 314.4 g/mol
A.K.A • Weed • Pot • Cannabis • Ganga • Grass • Reefer • Blaze • Skunk • Join • Green • Mary-jane • Herb • Chronic M A R I J U A N A
HOW IT WORKS Inhibitoryneurotransmitter made by your body, anandamide • Mimics NT anandamide (produced by body) • Binds to cannabinoid receptors,affects CNS + PNS • Inhibitory effects (hyperpolarizes postsynaptic cells, IPSP) Synthetic or phytocannabinoid THC Cannabinoid Receptor
CANNABINOID SYNAPSE NORMAL SYNAPSE
MEDICINALORMISUSED ????????? • TCH exposure has developmental consequences: affects cognitive abilities/IQ if used regularly in teens • Children exposed to marijuana in the womb have an increased risk of problems with attention, memory, and problem-solving • Not “addictive” (induces withdrawal symptoms) but people can become dependant • Augment schizophrenic tendencies
SOURCES • https://www.vice.com/en_us/article/bnp4bv/how-and-why-your-brian-makes-its-own-cannabinoids • http://headsup.scholastic.com/students/the-science-of-marijuana • https://www.livescience.com/24553-what-is-thc.html • https://www.drugabuse.gov/publications/drugfacts/marijuana • http://www.emcdda.europa.eu/publications/drug-profiles/cannabis • https://www.southcountymeds.com/how-thc-works-in-the-body/ • https://www.drugabuse.gov/related-topics/adolescent-brain/longitudinal-study-adolescent-brain-cognitive-development-abcd-study • http://thelancet.com/journals/lancet/article/PIIS0140-6736(10)60935-X/fulltext • http://reset.me/story/anandamide-putting-the-bliss-molecule-to-work-for-your-brain/ • http://headsup.scholastic.com/students/the-science-of-marijuana • http://headsup.scholastic.com/students/endocannabinoid