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Herpesviridiae

Herpesviridiae. Crista Wagner. Herpesviridae. double-stranded DNA genome enveloped 150-200 nm. Herpesviridae Taxonomy. Herpesviridae is a viral FAMILY genera of note Simplexvirus oral & genital herpes Varicellovirus chicken pox & shingles Cytomegalovirus immunocompromised individuals.

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Herpesviridiae

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  1. Herpesviridiae Crista Wagner

  2. Herpesviridae • double-stranded DNA genome • enveloped • 150-200 nm

  3. Herpesviridae Taxonomy • Herpesviridae is a viral FAMILY • genera of note • Simplexvirus • oral & genital herpes • Varicellovirus • chicken pox & shingles • Cytomegalovirus • immunocompromised individuals

  4. Herpesviridae Characteristics ~100 known named for spreading (herpetic) look of cold sores alternating active & latent infection • latent in nerve cells • active in epithelial tissue • no genome integration

  5. Disease Progression: Chicken Pox

  6. ViralReproduction

  7. HSV Infection of the Neonate 1/3000 US deliveries 70% are HSV-2 disease manifestation skin, eye & mouth disease skin lesions mortality rate 0% encephalitis central nervous system mortality rate 15% disseminated infection central nervous system multiple organ systems mortality rate 60% antiviral therapy (acyclovir)

  8. My Questions and Answers Question: What is the family Herpesviridae named for? Answer: The spreading look of cold sores No, no. Never, never do you want to have this slide as part of your presentation!!!

  9. Herpesviridae Characteristics ~100 known named for spreading (herpetic) look of cold sores alternating active & latent infection latent in nerve cells active in epithelial tissue no genome integration THIS is how you could answer questions as part of your presentation… Use animations for emphasis.

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