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Aspirin

Aspirin. A medical miracle. Source: http://jakeandkims.blogspot.com/2010/07/medicine-highlight-aspirin.html. Index. Reason for this topic History Chemistry of aspirin Uses Contra-indications Side effects Conclusion Questions, discussion. Why talk about aspirin?.

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Aspirin

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  1. Aspirin A medical miracle • Source: http://jakeandkims.blogspot.com/2010/07/medicine-highlight-aspirin.html

  2. Index • Reason for this topic • History • Chemistry of aspirin • Uses • Contra-indications • Side effects • Conclusion • Questions, discussion

  3. Why talk about aspirin? • Most people come across aspirin • You can teach an old dog new tricks!

  4. History • Hippocrates, father of medicine • Left records of relieving pain

  5. History • Hippocrates, father of medicine • 460 – 377 BC

  6. History • Hippocrates of Kos

  7. History • Hippocrates of Kos

  8. 1829 • Hippo-crates used the willow tree

  9. 1829 • It’s in willow tree bark

  10. 1829 • It’s salicin does the job! • But… side effects

  11. 1853 • France: Charles Frédéric Gerhardt neutralizes salicin with: • sodium • acetyl chloride

  12. 1853 • France: Charles Frédéric Gerhardt neutralizes salicin with: • sodium • acetyl chloride

  13. 1900 • Germany: Felix Hoffmann • Bayer patents the drug • Its name: aspirin

  14. 1900 • Germany: Felix Hoffmann • Bayer patents the drug • Its name: aspirin

  15. 1900 • Germany: Felix Hoffmann • Bayer patents the drug • Its name: aspirin

  16. Chemistry • salicylic acid

  17. Chemistry • acetic anhedryde

  18. Chemistry • aspirin

  19. Uses • Various pains, e.g. • painful periods • headaches • Fever • Stroke • Heart attack and heart attack prevention • Arthritis • Prevention of blood clots

  20. Special case 1829 • Stopping a heart attack • Advice: • Have aspirins ready • Chest pains? Chew one

  21. Side effects • Abdominal pains, cramps • Stomach irritation • Heartburn • Nausea/vomiting

  22. When not to use • On women • during pregnancy, especially after 6 months • when breastfeeding • On children • In case of: • Salicates allergy • Ulcers • Bleeding disorders

  23. Properties • Aspirin is absorbed in stomach

  24. Functions • Decreasing pain • Decreasing fever • Preventing blood clots • Countering strokes and arthitis

  25. More • http://www.periodicvideos.com/videos/mv_aspirin.htm • http://en.wikipedia.org/wiki/Aspirin

  26. Any questions?

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