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Notes: The Stomach. Tuesday 1-5-2010. (1) Overall Function. Break down “bolus” from esophagus. Metabolize ALL Carbohydrates. Begin Protein Metabolism. Turn “bolus” into liquid Small Intestine. (2) The Stomach as a Chamber.
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Notes: The Stomach Tuesday 1-5-2010
(1) Overall Function • Break down “bolus” from esophagus. • Metabolize ALL Carbohydrates. • Begin Protein Metabolism. • Turn “bolus” into liquid Small Intestine
(2) The Stomach as a Chamber • Stomach can contain up to 1.5L of food without pressure changes. • Feelings of discomfort come from irritants + too much food • Stomach composed of excess tissue Folds of Tissue = Rugae • Folds allow the stomach to expand • Folds also contain secretion glands • Food sits in the stomach for 3-4 hours • Depends on Amount & Type of food
(3) Contraction & Churning • Stomach composed of smooth muscle: • Contains 3 layers of muscle = STRONG • Contracts via peristalsis • Peristalsis used to Toss & Churn (not squeeze through). • Like Shake & Bake • Contractions stimulated by release of Serotonin from Rugae.
(4) Release of Gastric Juice • Gastrin (hormone) released from G-Cells within Rugae: • Triggered by smell + taste of food • Triggered by increase in pH • Gastrin stimulates release of HCl = Decreasing pH: • Proteins & Carbohydrates Metabolized • Small & Large Intestine stimulated
(5) Gastric Juice • HCl = Hydrochloric Acid • Pepsin = Enzyme = Breaks down protein • Rennin = Enzyme = Breaks down protein • Muccin = Mucus = Lubricate Food Mass
(6) Protein Metabolism • Proteins take a lot of Gastric Juice to Metabolize. • Breaking Down Proteins releases H+ ions. • Decreases pH of stomach. • G-Cells stop releasing gastrin HCl stopped.
(7) Exiting the Stomach • The mass leaving the stomach is called “Chyme”: • Mostly liquid Liquids leave first! • Solids are left behind until broken down • Approximately 3mL of food leaves at one time…. • Food Exits the Pyloric Sphincter • Chyme dumped into Small Intestine