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CHAPTER 26

CHAPTER 26. BONES JOINTS SOFT TISSUE TUMORS. BONES, JOINTS, SOFT TISSUE TUMORS. BONES JOINTS SOFT TISSUE TUMORS. BONES. NORMAL PATHOLOGY. BONES - NORMAL. MODELING/REMODELING GROWTH/DEVELOPMENT. PATHOLOGY. DEVELOPMENTAL/ACQUIRED FRACTURES OSTEONECROSIS (AVASCULAR NECROSIS)

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CHAPTER 26

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  1. CHAPTER 26 BONES JOINTS SOFT TISSUE TUMORS

  2. BONES, JOINTS,SOFT TISSUE TUMORS • BONES • JOINTS • SOFT TISSUE TUMORS

  3. BONES • NORMAL • PATHOLOGY

  4. BONES - NORMAL • MODELING/REMODELING • GROWTH/DEVELOPMENT

  5. PATHOLOGY • DEVELOPMENTAL/ACQUIRED • FRACTURES • OSTEONECROSIS (AVASCULAR NECROSIS) • INFECTIONS • TUMORS • MISC. TUMORS

  6. GENETIC/ACQUIRED • NUCLEAR PROTEIN/ DEFECTS • HORMONE DEFECTS • STRUCTURAL PROTEIN DEFECTS • METABOLIC PATHWAY DEFECTS • MACROMOLECULE DEGRADATION • DECREASED BONE MASS • OSTEOCLAST DYSFUNCTION • ABNORMAL MINERAL HOMEOSTASIS

  7. NUCLEAR PROTEINSTRANSCRIPTION FACTORS

  8. HORMONE DEFECTS

  9. STRUCTURAL PROTEINDEFECTS • COLLAGEN DESEASE, TYPE 1 (OSTEOGENESIS IMPERFECTA) • TYPES 2, 10, 11

  10. DEGENERATION ofMACROMOLECULES • MUCOPOLYSACCHARIDOSES

  11. METABOLIC PATHWAYDEFECTS • OSTEOPETROSIS

  12. DECREASED BONE MASS • OSTEOPOROSIS

  13. OSTEOCLAST DYSFUNCTION • PAGET DISEASE (Osteitis Deformans)

  14. ABNORMAL MINERALHOMEOSTASIS • RICKETS/OSTEOMALACIA • HYPERPARATHYROIDISM • RENAL OSTEODYSTROPHY

  15. RICKETS/OSTEOMALACIA

  16. HYPERPARATHYROIDISM

  17. RENALOSTEODYSTROPHY

  18. FRACTURES

  19. OSTEONECROSIS(AVASCULAR NECROSIS)

  20. OSTEOMYELITIS • PYOGENIC • TUBERCULOSIS • SYPHILIS

  21. PYOGENIC OSTEOMYELITIS

  22. TUBERCULOUSOSTEOMYELITIS

  23. SKELETAL SYPHILIS

  24. BONE TUMORS • BONE FORMING TUMORS • CARTILAGE FORMING TUMORS • FIBROUS/FIBRO-OSSEOUS TUMORS • MISC.

  25. BONE FORMING TUMORS • OSTEOMA • OSTEOID OSTEOMA/OSTEOBLASTOMA • OSTEOSARCOMA

  26. OSTEOMA

  27. OSTEOID OSTEOMA/OSTEOBLASTOMA

  28. OSTEOSARCOMA(OSTEOGENIC SARCOMA)

  29. CARTILAGE-FORMINGTUMORS • OSTEOCHONDROMA • CHRONDROMA • CHONDROBLASTOMA • CHONDROMYXOID FIBROMA • CHONDROSARCOMA

  30. OSTEOCHONDROMA

  31. CHONDROMA

  32. CHONDROBLASTOMA

  33. CHONDROMYXOID FIBROMA

  34. CHONDROSARCOMA

  35. FIBROUS/FIBRO-OSSEOUSTUMORS • FIBROUS CORTICAL DEFECT (NON-OSSIFYING FIBROMA) • FIBROMA • FIBROUS “DYSPLASIA” • FIBROSARCOMA and MFH (MALIGNANT FIBROUS HISTIOCYTOMA)

  36. FIBROUS CORTICAL DEFECT(NON-OSSIFYING FIBROMA)

  37. FIBROMA

  38. FIBROUS DYSPLASIA

  39. FIBROSARCOMA and MFH

  40. MISC. TUMORS • EWING SARCOMA and PNET (PERIPHERAL NEURO-ECTODERMAL TUMOR) • GIANT CELL TUMOR • METASTATIC

  41. EWING SARCOMA

  42. PNET

  43. GCT (GIANT CELL TUMOR)

  44. METASTASES to BONE

  45. JOINTS • NORMAL • PATHOLOGY

  46. PATHOLOGY • ARTHRITIS • TUMORS

  47. ARTHRITIS • OSTEOARTHRITIS (DEGENERATIVE ARTHRITIS) • RHEUMATOID ARTHRITIS (RA) • JUVENILE RHEUMATOID ARTHRITIS • SPONDYLOARTHROPATHIES • INFECTIOUS • GOUT • PSEUDOGOUT

  48. OSTEOARTHRITIS(DEGENERATIVE ARTHRITIS)

  49. RHEUMATOIDARTHRITIS • Morphology • Joints • Skin • Blood Vessels • Clinical Course

  50. JUVENILE RHEUMATOID ARTHRITIS

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