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UNIBADAN BIOMEDICAL ENGINEERING: A DREAM COME True

UNIBADAN BIOMEDICAL ENGINEERING: A DREAM COME True. By Prof. Akinwale COKER (UI Site Principal Investigator of Framework BME Grant). Presented at IBADAN CONFERENECE ON BIOMEDICAL ENGINEERING (Maiden edition) on 6 FEBRUARY, 2019. Email: Cokerwale@yahoo.com Phone: +2348092150892.

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UNIBADAN BIOMEDICAL ENGINEERING: A DREAM COME True

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  1. UNIBADAN BIOMEDICAL ENGINEERING: A DREAM COME True By Prof. Akinwale COKER (UI Site Principal Investigator of Framework BME Grant) Presented at IBADAN CONFERENECE ON BIOMEDICAL ENGINEERING (Maiden edition) on 6 FEBRUARY, 2019 Email: Cokerwale@yahoo.com Phone: +2348092150892

  2. Brief Introduction on the University of Ibadan • Why BME in Nigeria? • BME at Ibadan – Early Beginnings • Seminars, Workshops and Local Meetings • Development of Medical Devices • International Trainings of UI Faculty and Collaborations • BME Textbook from African Perspective • Curriculum Development for Masters Degree Programme in BME at Ibadan • Some Publications from the BME Projects • Impacts of BME Grant on UI • Future Perspectives • Concluding Remarks • Appreciation Presentation Outline

  3. Brief Introduction to University of Ibadan • University of Ibadan (UI) – Established in 1948, is the oldest University in Nigeria • University of Ibadan Postgraduate School is, well acknowledged within and outside the country as one of the largest in Africa and the flagship of Postgraduate Education in Nigeria • University of Ibadan produces an average of 3,000 Masters & 250 Ph.Ds every year  • The Times Higher Education in its World University Webtomeric Rankings for 2018 ranked UI as the best university Nigeria

  4. To expand the needed and available base expertise aimed at critical global health problems by development of trans-institutional problem-based research trainings that consolidate experts who collaborate on global health challenges. • Stimulate new knowledge, approaches and solutions in Global Health by putting “innovation” in the Global Health context • Merge global health research bodies amidst institutes by awareness boosts and increase interdisciplinary biomedical engineering capacity in Sub-Sahara Africa . • Nigeria cannot afford to be left behind in this global drive of using engineering to solve medical problems WHY BME IN NIGERIA?

  5. The Visit of the Current Nigeria’s Minister of Health (UI Immediate Past Vice Chancellor) – Professor Isaac Adewole to the Faculty of Technology in December 2010 on assuming office as VC • Passionate desire to commence Biomedical Engineering (BME) programme in UI expressed by the VC • Adhoc Curriculum Committee chaired by Professor Akinwale Coker was set up in 2011 to fashion a Master Programme in Biomedical Engineering • However, D43 BME Framework Grant (about 1.2 USD) awarded by US-based National Institutes of Health in 2013 to the consortium of Northwestern University Illinois, US, and Universities of Ibadan, Lagos and Cape Town gave fresh impetus to these efforts and widened the initial vision. BME at Ibadan – Early Beginning

  6. First BME Seminar in 2012 (3-day seminar) • Organised under the auspices of Medical Education Partnership Initiative in Nigeria (MEPIN), College of Medicine, University of Ibadan. Faculty of Technology Staff researching in areas related to BME were invited and they fully participated. • At the seminar, problems and challenges being experienced in Nigerian Hospitals were identified and possible engineering solutions proffered. • Two major projects which were selected based on crucial needs were - Infant Warming Device(for surgical neonates) and the Muscle Stimulator (for Anorectal Malfunction Surgery). Seminars, Workshops and Local Meetings

  7. Consequent upon the decision reached at the meeting in 2012 to develop the selected projects, the foci and venue of two workshops were set as follows: WORKSHOP 1 (1-5 July, 2013 @ University College Hospital (UCH) and University Health Services (UHS), Jaja clinic) • Agenda: Temperature Regulation in Surgical Neonates – Designing a Workable Solution for Resource-limited Settings WORKSHOP 2 (29 July – 2 August, 2013 @ UHS, Jaja clinic) • Agenda: Design of Muscle Stimulator for Anorectal Malfunction Surgery Seminars, Workshops and Local Meetings Contd.

  8. Research Visit of Five Graduate Students of Northwestern University (NU) to UI in July & August 2013 • Two sets of NU BME graduate students travelled down to the University of Ibadan for two different workshops on July 1-5 July, 2013 and on 29 July–2 August, 2013. They brainstormed with postgraduate students from the Departments of Civil Engineering, Electrical and Electronic Engineering, Industrial and Production Engineering as well as Mechanical Engineering. • UI Academic Staff from the Faculty of Technology and College of Medicine were on hand to facilitate and to mentor the students during each session of the workshops in July and August 2013. Seminars, Workshops and Local Meetings Contd.

  9. BME Framework Grant Inception Workshop at Ijebu-Ode, Nigeria (October 28 – 30, 2013) coordinated by the University of Ibadan after the notice of award from NIH was received by our US partner at Northwestern University in August 2013. • Agenda: Developing strategies for achieving the three objectives of the 5-year Grant • The objectives of the Grant are:- • To establish new and enhance existing training programmes in Biomedical Engineering in Sub-Saharan Africa • To train biomedical engineers and medical doctors to evaluate newly-developed testing and therapeutic devices • To train post graduates from business schools to scale up development and launch healthcare products Seminars, Workshops and Local Meetings Contd.

  10. D43 Frameworks Grant Workshop/Training held at Lagos University Teaching Hospital, (LUTH), University of Lagos (September 14 – 18, 2015) • Reports from former trainees at UCT and Northwestern University • Shared Insights and experiences as regards project development from design process and marketing of products • This training gave birth to three Seed Awards, after a Mini Hack-A-Thon session • Significant progress have been made on the Small Animal Cage project which is the Seed Award of the UI Team • Outlines for the BME Textbook for Africa were proposed Seminars, Workshops and Local Meetings Contd.

  11. D43 Frameworks Grant Workshop/Training held CESDEV, Bodija, Ibadan (29 – 31 August, 2016) • More reports from former trainees at UCT, Uganda, Ethiopia and Northwestern University • Presentations on BME Projects developed by Faculty Members • Update on Seed award project and 1st BME Textbook in Africa • Proposal for Launching of the 1st BME Journal in Africa Seminars, Workshops and Local Meetings Contd.

  12. Devices developed by UI Faculty members with inputs from NU • Warming device for surgical neonates • Needle crushing device • Muscle Stimulator for Anorectal Malformation Surgery • Animal Cages • Diversionary Distraction Technological Device for Burns Management • Design and Fabrication of Phototherapy Lamp Development of Medical Devices

  13. Infant Warming Pad – The Prototype

  14. Muscle Stimulator - Design stages

  15. Exudate absorbed by the Gamgee may reach surface – “Strikethrough, which is an infection risk.” • Task: Detect imminent strike- through, so that dressing may be changed before strikethrough. • Low cost, minimal additional work for staff. DIVERSIONARY DISTRACTION TECHNOLOGICAL DEVICE FOR BURNS MANAGEMENT

  16. Needle crushing device

  17. PhototherapyLamp

  18. Prototype of Animal Cage

  19. The BME Grant has created the opportunity for the Training of UI Faculty Members at US, South Africa, Tanzania, Uganda, Zambia, Malawi, Burkina Faso and Ethiopia between 2013 and 2018. Up to 22 academic staff (3 Professors, 10 Senior Lecturers, and 9 Lecturers) from Faculties of Technology, Science, Public Health, Clinical Sciences, Dentistry, Pharmacy, Veterinary Medicine, Social Sciences, Economics and Law travelled for the international training. Over 30 other academic staff from same Faculties attended national trainings held at Lagos, Ijebu Ode and Ibadan between 2013 and 2017. International AND NATIONAL Trainings of UI Faculty Members and Collaborations

  20. CHAPTER OUTLINES 1. Introduction 2. Biomedical Engineering in Africa 3. Needs Assessment 4. Design Process 5. Entrepreneurship 6. Legal Implications for Biomedical Engineering 7. Ethics and Engineering 8. Interdisciplinary Approaches to Biomedical Engineering 9. Culture and Social Issues for Biomedical Engineering 10. Funding for Biomedical Engineering 11. Managing Biomedical Engineering Products, Processes and Assets The book’s foreword is being written as I speak, preparatory to its coming out before June 2019. BME Textbook from African Perspective

  21. Committee Report approved at the Board of Faculty of Technology in 2015 and finally at UI Senate in January 2016 • Advertisement of the Master BME Programme on UI Website in 2017 attracted a good number of applications with variety of backgrounds. • Master Programme of a duration of 4 semesters began in February 2017. Post Graduate Certificate & Post Graduate Diploma in BME for duration of 1 & 2 semesters respectively also awardable. • The first (pioneer) set of students are due to graduate in few months time while the second set are also around, taking their course works. Curriculum Development for Masters Degree Programme in BME at Ibadan

  22. Biomechanics Clinical Engineering Imaging Modelling of Biomedical Processes Biomedical materials Biotechnology and Bio materials Engineering Areas of Specialisation

  23. The Facilitators of this Interdisciplinary Graduate Programme are Academic Staff from 10 Faculties out of the 13 Faculties existing within UI: • Technology • Sciences • Basic Medical Sciences • Clinical Sciences • Public Health • Dentistry • Pharmacy • Veterinary Medicine • Law and • The Social Sciences • Economics

  24. Microchannel • E. Ige, A. Dare, and A. Coker • University of Ibadan, Ibadan, Nigeria • Design andAbstracts: • Biomedical Engineering Society (BMES) 2014 meeting San Antonio, TX: Development of Design-Oriented BME Degree Programs in Nigeria • M. Glucksberg1, A. Coker2, A. Osuntoki3, T. Douglas4, and R. Murphy5 • 1Northwestern University, Evanston, IL, 2University of Ibadan, Ibadan, Nigeria, 3University of Lagos, Lagos, Nigeria, 4University of Cape Town, Cape Town, South Africa, 5Northwestern University, Chicago, IL • Numerical Modeling of Magnetic Micropump for Biogenic Bulk Transport in a Biomimetic Construction of a Blood Glucose Meter for Use in Nigeria Some Publications from the BME ProjectS

  25. SOME PUBLICATIONS FROM THE BME PROJECTS CONTD. A. Zubair, O. Ibe, and A. CokerUniversity of Ibadan, Ibadan, NigeriaDesign and Construction of a Portable Low Cost Electrical Safety Analyzer for Biomedical Devices Biomedical Engineering Society 2015 Annual Meeting in Tampa, FL: CFD-based Investigation of Pulse Wave and Arterial Wall Compliance in Saccular Aortic AneurysmAdemola Dare, OlubunmiIge and Akinwale, Coker2016 ASEE International Forum, New Orleans, LA:

  26. Developing Innovative Interdisciplinary Biomedical Engineering Programs in Nigeria: Lessons LearnedDavid W. Gatchell, Ph.D., Northwestern UniversityRobert Linsenmeier, Northwestern UniversityMatthew R. Glucksberg, Northwestern UniversityRobert L. Murphy, Northwestern UniversityAkinwale O. Coker, University of IbadanAkinniyi A. Osuntoki, University of Lagos, Lagos, Nigeria • 18th Congress of International Society for Burns Injuries (ISBI) 2016 Miami, Florida: • Indicator for Imminent Strikethrough of Wound Dressings. J. Goergen, A. Brikha, M. Glucksberg, A. Michael • Biomedical Engineering Society (BMES) Annual Meeting 2016 Minnesota, MN: SOME PUBLICATIONS FROM THE BME PROJECTS CONTD.

  27. Collaborations to Support Innovation in Biomedical Engineering in Africa M. Glucksberg, A. Coker, A. Osuntoki, T. Douglas, D. Gatchell and R. Murphy • Engineering Inclusive and Conducive Learning Environment for Mobility – Challenged Students: A Case Study Evaluation of a Nigerian UniversityAbel Olorunnisola • Design and Fabrication of Needles and Sharps Crusher for Sustainable Management of Biomedical Waste in Nigeria • Akinwale Coker, Charles Akintunde and Mynepalli Sridhar • Experimental Biology, Chicago 2017: • Amelioration of Sodium Fluoride-induced hypertension, cardio-renal oxidative stress and genotoxicity by Azadirachtaindica through antioxidant and extracellular signal-regulated kinase (ERK) 1/2 signalingOlumuyiwaAbiolaAdejumobi, University of Ibadan • World Health Organization (WHO) Global Forum on Medical Devices, Geneva, Switzerland, May 2017: • Design and Fabrication of Needle CrusherAkinwale Coker1, Charles Akintunde1, Chibueze Ache1, Mynepalli Sridhar1, Taiwo Hammed2, Tania Douglas2, Robert Murphy31University of Ibadan, Ibadan, Nigeria, 2University of Cape Town, Cape Town, South Africa3, Northwestern University, Chicago, Illinois, USA SOME PUBLICATIONS FROM THE BME PROJECT CONTD.

  28. Warming Solution for Neonatal Surgeries in Nigeria • Taiwo Lawal1, Akinwale Coker1, Robert Murphy2, Matthew Glucksberg2, David Gatchell2 • 1University of Ibadan, Ibadan, Nigeria and 2Northwestern University, Illinois, USABME training and BMES Conference, Fall 2017: • Leveraging on North-South Collaboration to Develop Biomedical Engineering Education and Practice in NigeriaAkinwale Coker1, Chucks Diji1, Sunday Adesogan1, Abel Olorunnisola1, Matthew Glucksberg2, David Gatchell2, Robert Murphy2 • 1University of Ibadan, Ibadan, Nigeria, 2Northwestern University, Illinois, USA • Green synthesis of Curcuma longa silver nanoparticles and its antimicrobial evaluationOdeniyi1, O.A, Adebayo-Tayo1, B.C, Coker2, M.E, Omilegan O.M11Department of Microbiology, Faculty of Science, University of Ibadan, Nigeria, 2Department of Pharmaceutical Microbiology, Faculty of Pharmacy, University of Ibadan, Nigeria • Design and Fabrication of Indigenous Phototherapy Equipment for Treating Neonatal Jaundice in NigeriaMynepalli K. C. Sridhar2,3, Hammed B. Taiwo2,3, Akinwale O. Coker1,4 SOME PUBLICATIONS FROM THE BME PROJECTS CONTD

  29. 1Biomedical Engineering Group, 2Renewable Resources Centre, Department of 3Environmental Health Sciences, Faculty of Public Health, College of Medicine, 4Department of Civil and Environmental Engineering, Faculty of Technology, University of Ibadan, Ibadan, Nigeria • BMES Conference 2018, Atlanta, GA • Design and Fabrication of an Indigenous Baby Incubator for Neonates in Nigeria • Mynepalli Sridhar, Akinwale Coker, Idowu Ayede and Hammed B. Taiwo. • University of Ibadan., Ibadan, Nigeria. • Journal Articles • Akinwale Coker (2018). Negative impacts of waste on human health and environment in Nigeria’s urban areas: Innovative solutions to the rescue. Global Health Innovation, 1(2), 1-3. DOI: 10.15641/ghi.v1i2.689. • Zubair, A. R. & C. O. Adebayo, E. U. Ebere-Dinnie & A. O. Coker (2015). Development of Biomedical Devices in Africa for Africa: A Blood Glucose Meter. International Journal of Electrical and Elect ronic Science, Vol. 2 No. 4, 102-108. SOME PUBLICATIONS FROM THE BME PROJECTS CONTD.

  30. Through the BME Grant, the following have so far been achieved: • Establishment of BME Programme at UI • Training in Nigeria and overseas of UI Staff and capacity building for Faculty Members • Introduction of user-based design projects in the postgraduate degree programme in UI • Enhanced interaction between the College of Medicine and the Main Campus of UI where most other Faculties are based • Stimulation of ‘home grown’ researches in development of medical diagnostics devices • Contribution to the about-to-be published 1st BME Textbook written with Africa’s perspective. UI Faculty members contributed in more than half of the chapters of the both. • Contribution to the first BME Journal in Africa (Global health Innovation) Website: https://journals.uct.ac.za/index.php/GHI Impacts of BME Grant on UI and Opportunities Created by Trainings for Staff

  31. Training of more Academic Staff from UI • Floating of a Nigeria-based Biomedical Engineering Journal • Integration into International BME societies/organizations • African Biomedical Engineering Consortium (ABEC) • Innovators School Programme (ISS) • Publication of the first BME Textbook written with African perspective • Completion of ongoing BME projects and development of more medical devices • Commercialization of products • Patenting of developed medical devices • Publishing of more scientific papers in High-Impact Journals • Leveraging on new Grants on BME especially the recent awarded C-THAN Grant (about 7.6 million USD) to the consortium of Northwestern University, UI, UNILAG, UNIJOS, UCT, Stellenbosch University and two other Universities in Mali and Tanzania. Future Perspectives

  32. The milestone achievements thus far at UNIBADAN BME has helped in; • Creating awareness and opportunities on BME through multi-disciplinary approach. • Developing capacity to harness from ample potentials and resources through progressive research for better healthcare in Nigeria and Africa at large. ConcludingRemarks

  33. Fogarty International Center, National Institutes of Health, Maryland, USA • Immediate past Vice Chancellor of UI – Prof. Isaac Adewole • Current Vice Chancellor of UI – Prof. Abel Olayinka • Former Deans of Faculty of Technology – Prof. A.E. Oluleye, Prof. O. Charles-Owaba & Prof. E.A. Ajav • Current Dean of Faculty of Technology –Prof. K. Ogedengbe • Our Research Partners in Northwestern University, University of Cape Town and University of Lagos • University of Ibadan BME Team Appreciation

  34. Thank you

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