Targeted therapy Dr. Murali Subramanian Medical Oncologist

1. Targeted therapy www.drmuralisubramanian.com

2. Presentation Overview TODAY'S DISCUSSION What is targeted therapy? What are the types of targeted therapy? How does targeted therapy work against cancer? What are the side effects of targeted therapy? How is targeted therapy given? How often should the patient receive targeted therapy?

3. What is targeted therapy? Targeted therapy refers to a type of cancer treatment that specifically targets certain molecules or genetic mutations that are involved in the growth and survival of cancer cells. Unlike traditional chemotherapy, which can affect both healthy and cancerous cells, targeted therapies are designed to selectively attack cancer cells while minimizing damage to normal cells.

4. What are the types of targeted therapy? There are two types of targeted therapy • Small-molecule drugs • Therapeutic antibodies

5. How does targeted therapy work against cancer? • - Targeted therapy selectively targets molecules or genetic abnormalities involved in cancer cell growth and survival. • - It disrupts specific signaling pathways and inhibits tumor growth. • - Some targeted therapies block angiogenesis, starving the tumor cells of nutrients. • - They can interfere with cell division, preventing the tumor cells from multiplying. • - Targeted therapies promote apoptosis, leading to self-destruction of cancer cells. • - They can overcome resistance to other cancer treatments by targeting specific mutations or alterations.

6. What are the side effects of targeted therapy? Some of the Targeted therapy side effects include diarrhea, mouth sores, loss of hair, fatigue, and skin problems such as rashes or dry skin.

7. How is targeted therapy given? Targeted therapy is given either as Oral pill or Monoclonal antibodies which is given intravenously.

8. How often should the patient receive targeted therapy? How long the patient receives targeted therapy depends on the stage of cancer and how the patient’s body responds to the treatment. Targeted therapy can be given in cycles( This refers to a period of treatment followed by a period of rest ) or oral continuous therapy.

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